Miruvor
ME/CFS Severe → substantialIll for 40 yearsNeeds ongoing treatment

Tricyclic Antidepressants Work for Me

Condition
ME/CFS
At worst
Severe (mostly bedbound)
Ill for
40 years
Published
Undated

Summary

RuralRick woke up with sudden-onset CFS 40 years ago and spent 4 untreated years severely affected before a second tricyclic antidepressant (after a first failed) brought remission within about a week at 125-150mg. He has maintained that remission on a 25-75mg daily maintenance dose for decades, with symptoms reliably returning whenever the dose drops too low, so the drug controls rather than cures the condition.

Read it in their words

forums.phoenixrising.me

Symptoms mentioned

Symptoms: Anxiety & low mood.