Miruvor

Nimodipine / tadalafil / vasoactive

6 people describe trying Nimodipine / tadalafil / vasoactive, all with ME/CFS.

17%
recovered fully or nearly
1 of 6
50%
improved (substantial or partial)
3 of 6
17%
relapsed
1 of 6
16%
no benefit
1 of 6

How it went

Did it last?

  • 1 of 6 said the benefit wore off: the one who relapsed.
  • 1 of 6 needed to keep doing it to stay well.

Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.

Outcome describedAccountsShare
Full recovery00%
Near-full117%
Substantial233%
Partial117%
Relapsed117%
No benefit117%

Only 6 accounts. Treat these percentages as anecdotes, not rates.

By how ill people were

Severity at worstHow it wentnRecovered
Moderate30%
Severe250%

1 accounts don’t say how ill the person was.

Who published these accounts

Sells a treatment or program1 accounts
0%
Independent (blog, forum, news)5 accounts
20%

Right-hand number: share describing a full or near-full recovery. Pages that sell something, and advocacy sites, tend to publish only the successes.

All 6 accounts

  • the best treatments I've found

    Substantial ME/CFS forums.phoenixrising.me · sells Aug 2023

    Shanti1 credits this vasodilator/oxygen combination with improving brain circulation and says episodes of feeling oxygen-starved, once frequent, are now rare, describing sustained improvement "over time as underlying conditions addressed." No specific doses…

  • A Calcium Channel Blocker for ME/CFS and Fibromyalgia? Nimodipine Pt. II

    No benefit ME/CFS Moderate healthrising.org Jun 2019

    Nimodipine, a dihydropyridine calcium channel blocker, caused a severe adverse reaction in this patient after just two tablets, one per day. Illness duration before the trial is not stated. She experienced paralysis in her arms and legs, which reversed only…

  • Nimodipine use in M.E./CFS - a comprehensive guide (S. Parker, MBA, BSc, January 2014)

    Substantial ME/CFS SevereIll 15 years forums.phoenixrising.me Jan 2014

    Nimodipine, titrated from 45mg up to 90mg daily taken as 30mg three times a day, took her from 20-25% of well to 80-90% of well with mental clarity nearing 90%. She had been ill since 1991 and began the drug in 2006, holding the gain for more than seven…

  • NIMODIPINE use in M.E. / CFS : A comprehensive guide. S. Parker (MBA, BSc) January 2014

    Partial ME/CFS Moderate forums.phoenixrising.me

    Amlodipine, a dihydropyridine calcium channel blocker, was taken for about a month by this ME/CFS patient in Australia. Illness duration before starting is not stated. Her POTS-type symptoms had started improving by the one-month mark. The post is written…

  • NIMODIPINE use in M.E. / CFS : A comprehensive guide. S. Parker (MBA, BSc) January 2014

    Relapsed ME/CFS ModerateEffect faded forums.phoenixrising.me

    Nimodipine, a dihydropyridine calcium channel blocker, gave this ME/CFS patient a "noticeable cognitive benefit" at an unspecified dose. Illness duration before starting is not stated. In a later update to the same thread, posted in 2021, they reported that…

  • NIMODIPINE use in M.E. / CFS : A comprehensive guide. S. Parker (MBA, BSc) January 2014

    Near-full ME/CFS Severe forums.phoenixrising.me

    Nimodipine, a dihydropyridine calcium channel blocker, was titrated from 15mg up to a maintenance dose of 90mg a day (30mg three times daily) over 7-plus years of treatment described in her own guide. She started at just 20-25% of normal functional capacity,…