Long COVID/ME-CFS Patient Goes into Remission After 3 Weeks on the Antiviral Sofosbuvir
- Condition
- Long COVID
- At worst
- Severe (mostly bedbound)
- Ill for
- 2 years
- Published
- Apr 2023
Summary
After 2 years of severe, housebound long COVID (POTS, MCAS, brain fog, gut issues, severe weight loss), this patient took standard-dose Harvoni (sofosbuvir/ledipasvir), an antiviral, for 3 weeks and reported the POTS, brain fog and MCAS symptoms resolving to a pre-COVID state within that period, planning several more weeks of treatment. The post explicitly flagged that only one month of remission had elapsed and relapse remained possible, so durability beyond that point is unconfirmed.
What they credit
Credits POTS medication, Antihistamines & MCAS, Antivirals, Sofosbuvir / maraviroc (off-label).
Symptoms mentioned
Symptoms: Brain fog, Gut problems, Mast cell (MCAS) & allergies, POTS & dysautonomia.
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