How it went
Did it last?
- 1 of 8 said the benefit wore off.
- 2 of 8 needed to keep doing it to stay well.
Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.
| Outcome described | Accounts | Share |
|---|---|---|
| Full recovery | 2 | 25% |
| Near-full | 1 | 12% |
| Substantial | 5 | 62% |
| Partial | 0 | 0% |
| Relapsed | 0 | 0% |
| No benefit | 0 | 0% |
Only 8 accounts. Treat these percentages as anecdotes, not rates.
By how ill people were
| Severity at worst | How it went | n | Recovered |
|---|---|---|---|
| Moderate | 1 | 0% | |
| Severe | 2 | 50% | |
| Very severe | 3 | 33% |
2 accounts don’t say how ill the person was.
Who published these accounts
Right-hand number: share describing a full or near-full recovery. Pages that sell something, and advocacy sites, tend to publish only the successes.
How often it comes up
Posts that mention Fludrocortisone / Florinef, per 1,000 posts each year. Hover a point for the count.
Show as a table
| Year | Posts mentioning it | All posts | Per 1,000 |
|---|---|---|---|
| 2009 | 0 | 184 | 0.0 |
| 2010 | 0 | 682 | 0.0 |
| 2011 | 1 | 704 | 1.4 |
| 2012 | 12 | 1,491 | 8.0 |
| 2013 | 0 | 1,708 | 0.0 |
| 2014 | 2 | 2,352 | 0.9 |
| 2015 | 18 | 2,158 | 8.3 |
| 2016 | 1 | 1,431 | 0.7 |
| 2017 | 3 | 3,110 | 1.0 |
| 2018 | 0 | 2,201 | 0.0 |
| 2019 | 4 | 1,075 | 3.7 |
| 2020 | 6 | 2,581 | 2.3 |
| 2021 | 10 | 1,867 | 5.4 |
| 2022 | 0 | 1,166 | 0.0 |
| 2023 | 2 | 1,000 | 2.0 |
| 2024 | 0 | 1,237 | 0.0 |
| 2025 | 0 | 1,019 | 0.0 |
| 2026 (so far) | 0 | 840 | 0.0 |
Posts in the forum threads we archived, 26,806 in all, counted per year. A mention means the post names the treatment, not that the writer took it. These threads all contain a recovery story, so they show what those communities discussed, not everyone with ME/CFS or long COVID. All trends
All 8 accounts
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I replace ALL my hormones. This brought me back to life.
thingsvarious systematically replaced testosterone, cortisol, thyroid, growth hormone and aldosterone after years of "nightmare"-level fatigue, largely managing it himself because, in his words, "many endocrinologists are shit." He says his energy moved from…
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Long-Term Daily mHBOT and Full Recoveries w/ Ongoing Maintenance
used_to_race combined daily hydroxychloroquine with mHBOT sessions 3-4 times a week for 45-90 minutes, plus fludrocortisone for POTS, and reported bad days becoming much less frequent, with capacity for 76-mile cycling weekends and full-time work plus…
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Health Update #4: Recovery is a %*#*&$@!
Jennifer Brea had been managing severe ME for about 8 years with Valcyte, Valtrex, Mestinon, and fludrocortisone plus mold avoidance, which had only brought her from severe to moderate; in November 2018 she underwent three surgeries over six weeks — a…
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Anyone else here have MCS too?
Followed the Pall Protocol, a methylation-support supplement regimen, then added dysautonomia treatment with fludrocortisone and verapamil, for severe MCS with CFS. Beforehand had near-syncope events, needed an epipen and sudafed, and was essentially…
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how did you get out of "bedridden level" ??(even if you are still sick)
Reports going from bedridden to walking a mile and a half the next day after starting Florinef, Midodrine and a beta-blocker for orthostatic symptoms. Frames it as trial-and-error ("the trick is to try things") with no dose, duration or durability detail given.
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Stinging Her Way Back to Health
Nancy developed chronic fatigue syndrome in 1994 and experienced a relapse along the way. She credits bee venom therapy, which she says is not a cure but helped her get her life back, together with vitamin B12, hypnotherapy, guided meditation and…
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Cured Myself After 4 Years of CFS
Over about four years and more than $50,000 on doctors and supplements, this poster went from lying "almost paralyzed" to calling himself cured, crediting a stack that included DHEA (100mg/day, 200mg on exercise days), Florinef for low aldosterone,…
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3 Things that Help the Most!!
Manages orthostatic intolerance with midodrine, fludrocortisone, time-released potassium, salt tablets, 3 liters of water a day, deliberately reclining to rest, and a folding cane/stool for standing tasks. Says this combination substantially improves her…