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Long COVID Mild → somewhat betterIll 2.5 years before improving or writing

Long COVID with constant tiredness and severe anxiety, somewhat better after ketamine

Condition
Long COVID
At worst
Mild (working or studying, with limits)
Ill before improving or writing
2.5 years
Last post
May 2025
In their words
  • Condition: Long COVIDI’ve had long covid for 2 yr 7 mo In context ↗
  • At worst: Mildthe frustration of not being able to do the things you enjoy, missing out on life, and feeling powerless and hopeless In context ↗
  • Now: Somewhat betterI have been slowly getting better ... it helped a lot, especially with the anxiety
  • Began after: COVIDI‘ve had long covid for 2 yr 7 mo In context ↗
Read from 4 of their posts and comments; links to the 4 this page draws on

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Summary

A Reddit user had long COVID for about two and a half years, with constant tiredness, severe anxiety, dread and panic, and depression that worsened when physical symptoms did. Activity had to be balanced because overdoing it brought payback. Medication did not really help, but a clinical course of ketamine helped a lot, especially the anxiety, though each session left them very tired for days and things worsened before improving gradually.

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What they tried

Also tried

ketamine treatment· Helped a lotmedication· No change
Their words about each treatment
  • medication · No changeAfter trying medication for a while and it not really helping In context ↗
  • ketamine treatment · Helped a lotI had a course of ketamine treatment in a clinical setting for my anxiety and depression, and it helped a lot, especially with the anxiety In context ↗

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happenedAfter
onsetLong COVID beganI‘ve had long covid for 2 yr 7 mo In context ↗
2025-03-30Slowly getting better over timeI have been slowly getting better In context ↗
2025-05-07Gradual improvement continuing after a clinical ketamine courseI’d say it was gradual and continued after I finished the course In context ↗Ketamine

Adverse events

  • Ketamine“I found the sessions made me very tired and it took me a few days to recover after each” In context ↗ Side effects
  • Ketamine“usually the more tired I am the more emotional and anxious I am, so it got worse before it got better after each session” In context ↗ Mood or psychiatric effects

Symptoms mentioned

Their words about their symptoms
  • Anxiety & low moodI have also had very bad anxiety with long covid ... my physical symptoms are worse, my depression gets worse too
  • Post-exertional malaiseActivity is such a balance - it’s good for the spirit to do things, but do too much and I pay the price afterwards In context ↗

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