ME/CFS with PEM, partly better after high-dose dexamethasone
- Condition
- ME/CFS
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- May 2026
In their words
- Condition: ME/CFS
PEM threshold and all other ME- symptoms
In context ↗ - Now: Somewhat better
had a very good response: A big Improvement PEM threshold and all other ME- symptoms.
In context ↗
Read from 1 of their posts and comments; links to the one this page draws on
Summary
A Reddit user with ME/CFS reported taking high-dose dexamethasone for 25 days and having a very good response: a big improvement in their PEM threshold and all other ME symptoms. They attributed the effect to dexamethasone, noting it is the most effective steroid at crossing the blood-brain barrier. No details on illness duration, baseline severity, or follow-up were provided.
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What they tried
What they credit
Their words about each treatment
- high dose dexamethasone · Helped a lot
I was 25 days on high dose dexamethasone and had a very good response: A big Improvement PEM threshold and all other ME- symptoms.
In context ↗
Approaches: Other drugs and medicines
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
A big Improvement PEM threshold
In context ↗
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