Long COVID
Outcome unclear
Long COVID with wired tiredness and poor sleep, tried high-dose melatonin and magnesium
- Condition
- Long COVID
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Sep 2026
In their words
- Condition: Long COVID
I was on Bupropion when I got Covid/long covid.
In context ↗ - Began after: COVID
I was on Bupropion when I got Covid/long covid.
In context ↗
Read from 5 of their posts and comments; links to the 5 this page draws on
Summary
Got long COVID while taking bupropion and stopped it a year in without noticing a difference. They described a wired, tired state with poor sleep, and credited high-dose melatonin (30 mg), tryptophan and magnesium with helping; later they took six or more a day. Guanfacine made them too tired to do anything or rest properly, and SSRIs had not helped over 10 years of use.
Ask Miruvor AI
What they tried
Also tried
Their words about each treatment
- Melatonin · Helped
High doses are quite nice for me.
In context ↗ - tryptophan · Helped
Of these I think tryptophan and magnesium are the most effective for me for the symptom you are describing.
In context ↗ - l-theanine · Helped
l-theanine (less noticeable effect for me, but lots of research supporting its calming effect on the body)
In context ↗ - magnesium · Helped
magnesium! (Magnesium glycinate is the most bang for your buck usually, but Magnesium Citrate works too.
In context ↗ - electrolytes (including potassium) · Not said
Also getting enough electrolytes, including potassium.
In context ↗ - THC/CBD gummies · Not said
Also, THC/CBD gummies at a low dose of THC (1-5mg) if you are somewhere that is allowed.
In context ↗ - guanfacine · Worse
the only one I’ve tried is guanfacine, which made me too tired to do anything while still not being able to rest properly
In context ↗ - SSRIs/SNRIs · No change
after 10+ years of experience with many different ones that all basically do the same thing ... they don’t really work.
In context ↗ - Bupropion · No change
I was on Bupropion when I got Covid/long covid.
In context ↗ - omega 3 fish oil · Helped
Yep, they help. For me, taking 6+ of them a day has noticeable benefits.
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | Got COVID-19 and went on to long COVIDI was on Bupropion when I got Covid/long covid.In context ↗ | |
| 2026-03-25 | supplements eased the wired, tired feelingOf these I think tryptophan and magnesium are the most effective for meIn context ↗ | |
| 2026-09-14 | high-dose fish oil gave noticeable benefittaking 6+ of them a day has noticeable benefitsIn context ↗ | Omega-3 and fish oil |
Adverse events
- Guanfacine“the only one I’ve tried is guanfacine, which made me too tired to do anything while still not being able to rest properly.” In context ↗ Side effects
- Melatonin“Sometimes I take less if I’ve been too sleepy for a few days” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Sleep problems
usually I’m in the wired/tired mode and can’t sleep well
In context ↗