ME/CFS
Outcome unclear
Unable to get off the couch with ME/CFS, no crash yet after dose increase
- Condition
- ME/CFS
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Jul 2025
In their words
- Condition: ME/CFS
Im 3 days in to 5mg/day and have been crashing out hard in the afternoon.. dead tired, cant get off the couch
In context ↗
Summary
A person began taking 5 mg/day in July 2025. Three days in they were crashing hard in the afternoons, dead tired and unable to get off the couch. After increasing the dose to 10 mg/day they reported no crash like the previous three days, though they said this was completely anecdotal. The crash had not occurred so far after the dose was raised.
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What they tried
Also tried
Their words about each treatment
- SS-31 · Worse
Im 3 days in to 5mg/day and have been crashing out hard in the afternoon.. dead tired, cant get off the couch
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | Where they were | After |
|---|---|---|---|
| 2025-07-28 | crashed in the afternoon on SS-31 5 mg/dayIm 3 days in to 5mg/day and have been crashing out hard in the afternoon.. dead tired, cant get off the couchIn context ↗ | Moderate | SS-31 (elamipretide) |
| 2025-07-28 | raised SS-31 to 10 mg/day and had no afternoon crashi increased to 10mg today and had so far had no crash out like the previous 3 days on lower dosesIn context ↗ | Not stated | SS-31 (elamipretide) |
Adverse events
- SS-31 (elamipretide)“Im 3 days in to 5mg/day and have been crashing out hard in the afternoon.. dead tired, cant get off the couch” In context ↗ Made symptoms worse