ME/CFS
No benefit
ME/CFS crash after general anaesthetic and Mounjaro, no improvement
- Condition
- ME/CFS
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Aug 2026
In their words
- Condition: ME/CFS
I've had a terrible summer, basically crash after crash
In context ↗ - Now: No benefit
I'm still having a bit of a nightmare tbh
In context ↗
Read from 6 of their posts and comments; links to the 6 this page draws on
Summary
An ME/CFS patient reported crashing for well over a month after a general anaesthetic and advised others to avoid it. In May 2026 they took Mounjaro and also started a microdose, and said it made them crash hard; they thought it may have begun a summer of crash after crash. By late August 2026 they were still having a difficult time and planned to try maintenance calories. They reported no improvement.
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What they tried
Also tried
manta pro· HelpedFreeze a bottle of water and put it in a pillow case· Helpedhibiscrub· HelpedGeneral anaesthetic· Much worsemounjaro· Much worseeating at a slight deficit· Not said
Their words about each treatment
- manta pro · Helped
Haven’t used my manta pro all summer because it’s been too hot which is a shame because it’s a great eye mask
In context ↗ - General anaesthetic · Much worse
General anaesthetic caused me to crash for well over a month fwiw I would avoid
In context ↗ - Freeze a bottle of water and put it in a pillow case · Helped
Freeze a bottle of water and put it in a pillow case - either put it between your thighs or under armpit - for me it’s been a game changer
In context ↗ - hibiscrub · Helped
Have you tried hibiscrub? It’s the only thing that has shifted fungal infection for me
In context ↗ - mounjaro · Much worse
Took mounjaro in may and it made me crash hard - started microdose also
In context ↗ - eating at a slight deficit · Not said
I did try continuing to eat at a slight deficit after I came of it but I’m still having a bit of a nightmare tbh
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened |
|---|---|
| 2024-09-26 | crashed for well over a month after a general anaestheticGeneral anaesthetic caused me to crash for well over a month fwiw I would avoidIn context ↗ |
| 2026-05 | started Mounjaro as a microdose and crashed hardTook mounjaro in may and it made me crash hard - started microdose alsoIn context ↗ |
| 2026-08-27 | a summer of crash after crash, still strugglingI’m still having a bit of a nightmare tbhIn context ↗ |
Adverse events
- “General anaesthetic caused me to crash for well over a month fwiw I would avoid” In context ↗ Made symptoms worse
- Tirzepatide (Mounjaro, Zepbound)“Took mounjaro in may and it made me crash hard - started microdose also - I’ve had a terrible summer, basically crash after crash” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Temperature regulation
Freeze a bottle of water and put it in a pillow case - either put it between your thighs or under armpit - for me it’s been a game changer
In context ↗