ME/CFS
No benefit
ME/CFS fatigue no better with Adderall, caffeine or modafinil alone
- Condition
- ME/CFS
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Apr 2026
In their words
- Condition: ME/CFS
I had adhd and cfs.
In context ↗ - Now: No benefit
I take about 60mg a day plus energy drinks and it doesnt seem to touch my fatigue most days.
In context ↗
Summary
User with chronic fatigue and ADHD said their fatigue was barely touched by about 60 mg of generic Adderall a day, caffeine and energy drinks. The only thing that put a dent in it was combining Adderall with modafinil 200 mg, but their doctor later refused to prescribe both. Modafinil alone made little difference. They also said their B12 was high and their neurologist told them to stop supplementing B vitamins, though they feel a difference when they don't take them.
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What they tried
Their words about each treatment
- adderall · Helped
my adderall (for adhd but helps slightly with the fatigue)
In context ↗ - caffeine and energy drinks · No change
copious amounts of caffeine throughout the day. And those barely scrape the surface
In context ↗ - b vitamins · Helped
My neurologist told me to stop supplementing b vitamins but I can literally feel the difference when I dont take them
In context ↗ - modafinil · Helped
The only thing that seemed to put a dent in the fatigue was when I was able to combo together my generic adderall and modafinil
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | ongoing chronic fatigue and ADHDchronic fatigue but high b12 levelsIn context ↗ | |
| — | combining Adderall with modafinil put a dent in the fatigueThe only thing that seemed to put a dent in the fatigue was when I was able to combo together my generic adderall and modafinil.In context ↗ | Modafinil / armodafinil |
| 2026-04-26 | doctor refused to prescribe Adderall and modafinil togetherBut my doctor now refuses to give me both even though they worked for me.In context ↗ | |
| 2026-04-26 | still taking about 60 mg Adderall a day plus energy drinksI take about 60mg a day plus energy drinks and it doesnt seem to touch my fatigue most days.In context ↗ |