Severe chronic fatigue with ME/CFS; Vyvanse helped at first, then stopped working
- Condition
- ME/CFS
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- May 2026
In their words
- Condition: ME/CFS
as someone who suffers from severe chronic fatigue AND adhd
In context ↗ - Now: Relapsed
It didn't last. The energy part... Your body will adjust and it will stop delivering that relief.
In context ↗
Read from 1 of their posts and comments; links to the one this page draws on
Summary
They had severe chronic fatigue alongside ADHD and had taken Vyvanse for years. At first the stimulant gave enough energy relief to show them what normal life felt like, but their body adjusted and the relief stopped, which they called heartbreaking. They advised taking it only when really needed to make it keep working a little longer.
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What they tried
What they credit
Their words about each treatment
- vyvanse · Helped
I take vyvanse have for ages ... It didn't last. The energy part... Your body will adjust and it will stop delivering that relief.
In context ↗
Approaches: Stimulants
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | severe chronic fatigue alongside ADHDas someone who suffers from severe chronic fatigue AND adhdIn context ↗ | |
| — | Vyvanse gave energy relief at firstIt let's you see what NORMAL life is like for everyone else.In context ↗ | Lisdexamfetamine (Vyvanse, Elvanse) |
| — | tolerance to Vyvanse; the energy relief fadedYour body will adjust and it will stop delivering that relief.In context ↗ | |
| 2026-05-30 | still severely fatigued, weighed down every dayThen it takes it away. It's heart breaking.In context ↗ |
Symptoms mentioned
Their words about their symptoms
- Muscle weakness
weighed down by 30 imaginary cinder blocks every day
In context ↗
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