ME/CFS with POTS and crashes after mild COVID, much better on Vyvanse and time
- Condition
- ME/CFS
- At worst
- Not stated
- Ill before improving or writing
- 3 years
- Last post
- Jun 2025
In their words
- Condition: ME/CFS
I’ve had CFS since COVID in 2020.
In context ↗ - Now: Much better
This is the first summer since 2020 I’ve actually sweated ... Progress has been so slow, I barely noticed it.
In context ↗ - Began after: COVID
I developed CFS after a mild COVID infection in 2020
In context ↗
Read from 7 of their posts and comments; links to the 4 this page draws on
Summary
They developed CFS after a mild COVID infection in late 2020. After an ADHD diagnosis around mid-2023, Vyvanse greatly improved their CFS symptoms, POTS and energy, though they still crashed if they overdid things. By June 2025 their sweating had returned after years of heat intolerance, they credited over half their recovery to time, and they described progress as slow.
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What they tried
What they credit
Also tried
Their words about each treatment
- Vyvanse · Helped a lot
6 months ago I was diagnosed with ADHD and started Vyvanse. The differences it’s made for my CFS is astoundinggg
In context ↗ - Adderall · Helped a lot
I take Vyvanse and Adderall everyday and it significantly improved my POTS and energy levels.
In context ↗ - prednisone · Worse
I’m more likely to crash after something like coffee (or the prednisone I’m currently taking 🙃)
In context ↗
Approaches: Stimulants
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. The chart starts 2.7 years after onset: the story doesn’t say how ill they were before that. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| late 2020 | mild COVID infection followed by CFSI developed CFS after a mild COVID infection in 2020In context ↗ | Not stated |
| around mid-2023 (6 months before February 2024) | ADHD diagnosis, started Vyvanse; large improvement in CFS symptoms and energy6 months ago I was diagnosed with ADHD and started Vyvanse. The differences it’s made for my CFS is astoundingggIn context ↗ | Mild |
| June 2025 | started sweating again after years of heat intolerance; slow ongoing changeThis is the first summer since 2020 I’ve actually sweatedIn context ↗ | Mild |
Adverse events
- Lisdexamfetamine (Vyvanse, Elvanse), Amphetamine salts (Adderall)“the stimulants can make me crash if I overdo it while I’m feeling good” In context ↗ Made symptoms worse
- Lisdexamfetamine (Vyvanse, Elvanse)“I had a few crashes in the beginning” In context ↗ Made symptoms worse
- Corticosteroid pulses“I’m more likely to crash after something like coffee (or the prednisone I’m currently taking 🙃) than Vyvanse” In context ↗ Made symptoms worse
- Lisdexamfetamine (Vyvanse, Elvanse), Amphetamine salts (Adderall)“I just have to make sure I eat as it’s wearing off or else I’ll crash hard.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
I just have to be careful because the stimulants can make me crash if I overdo it while I’m feeling good
In context ↗ - POTS & dysautonomia
I take Vyvanse and Adderall everyday and it significantly improved my POTS and energy levels
In context ↗ - Mast cell (MCAS) & allergies
I was diagnosed with POTS, hEDS, MCAS, and endometriosis since having COVID
In context ↗ - Temperature regulation
One of my most persistent long Covid symptoms has been heat intolerance and temperature dysregulation.
In context ↗
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