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ME/CFS Outcome unclear

ME/CFS and POTS after SSRI reaction; antidepressants made them sicker, now considering LDA

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Sep 2026
Read from 3 of their posts and comments; links to the 2 this page draws on

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Summary

Fell ill after a bad reaction to SSRIs, which they believe caused their POTS and started their ME/CFS; they also have OCD. Several antidepressants and related drugs made them sicker, in some cases permanently. By their latest post a psychiatrist had mentioned low-dose Abilify (LDA) as an off-label option, and they had heard LDA plus LDN can help ME/CFS and POTS; they were hopeful but skeptical.

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What they tried

Their words about each treatment
  • Antidepressants (unspecified) · WorseIn fact have made me sicker permanently in some accords. In context ↗

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happened
—became ill after a bad reaction to SSRIs, with POTS and ME/CFS symptomsI actually first got sick when I had a bad reaction to SSRIS and I belive it caused my POTS and was the start of MECFS. In context ↗
2026-09-05recently started LDN; prescribed low-dose Abilify but nervous to startI’ve been hearing that LDA + LDN can be affective treatments for MECFS and POTS so I’m hopeful but skeptical for sure. In context ↗

Adverse events

Symptoms mentioned

Their words about their symptoms
  • POTS & dysautonomiaI belive it caused my POTS and was the start of MECFS In context ↗

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