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Long COVID Moderate → no benefitIll for 18 months

About a year into long COVID with terrible fatigue, no improvement from routines or Zoloft

Condition
Long COVID
At worst
Moderate (mostly housebound)
Ill for
18 months
Last post
Feb 2026
In their words
  • At worst: Moderatemy mom who took care of so many of the basic living functioning things In context ↗
  • Now: No benefitI know I’ve regressed In context ↗
  • Began after: a vaccinationmy theory that my vax injury is more taking the path of creating havoc in my body from an immune response standpoint
  • Says they never had: BreathlessnessI don’t have chronic pain or *knock on wood* heart related symptoms like being out of breath for the simplest things.
  • Says they never had: Heart symptoms & palpitationsI don’t have chronic pain or *knock on wood* heart related symptoms like being out of breath for the simplest things.
  • Says they never had: Pain & fibromyalgiaI don’t have chronic pain
Read from 5 of their posts and comments; links to the 4 this page draws on

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Summary

A Reddit user with long COVID who attributed their illness to a vaccine injury was about a year in when they posted in late 2025, with terrible fatigue and, later, worsening anxiety but no chronic pain and no physical PEM they were aware of. They spent four months at the lake with their mother being cared for, then regressed after returning home. Habit routines gave them a rested feeling and restarting Zoloft slightly eased their anxiety.

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What they tried

Their words about each treatment
  • herbal tincture for EBV · No changesome tincture they ordered me that’s herbal made specifically for EBV ... I don’t think it’s done anything to help In context ↗
  • vitamin d/k · Not saidI’m on a few other basic immune system stuff and vitamin d/k In context ↗
  • slowing down / not fighting it · WorseI honestly think I’m worse once I found out about the reactivated EBV because I forced myself to slow down and not fight it In context ↗
  • daily routine and habits · Helpedthe habits became things that weren’t decisions or choices my brain was making about what’s next ... that gave me ao much of a rested feeling that I never expected In context ↗
  • verilux happy light · Helpedputting my verilux happy light on for 30 minutes while eating ... that gave me ao much of a rested feeling that I never expected In context ↗
  • ivermectin · No changeMy doctor didn’t prescribe any medication other than a too low dose of ivermectin ... I don’t think the ivermectin or the entire “treatment” plan he put me on In context ↗
  • Zoloft · Helpedive noticed a difference already albeit slightly In context ↗
  • another antidepressant · Not saidI have major depressive disorder - I’m on another antidepressant as well In context ↗
  • klonopin · Helpedtaking my klonopin on a semi-regular basis acted like a reset button for my anxiety In context ↗

Their path

Very severeSevereModerateMildNear normalRecovered

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.

Show as a table
WhenWhat happenedWhere they were
onsetillness onset, which they call a vaccine injuryThe first thing I said out loud was over a year ago ... I don’t feel sick usually but I never feel well. In context ↗Moderate
summer 2025four months at the lake with their mother caring for themspending ~4 months at the lake with my mom who took care of so many of the basic living functioning things so I could truly try to heal In context ↗Moderate
autumn 2025returned home after the summer and regressedso I know I’ve regressed and probably can’t heal in this environment In context ↗Moderate
2025-12-14small daily routines gave them a rested feelingthat gave me ao much of a rested feeling that I never expected In context ↗Moderate
2026-02-03restarted Zoloft for out-of-control anxiety; slightly better, still illive noticed a difference already albeit slightly In context ↗Moderate

Adverse events

  • Sertraline (Zoloft)“I did recently forget to take my Zoloft and had a hard time getting back on it without having severe nausea symptoms.” In context ↗ Gut side effects

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaiseI don’t think I have a physical manifestation of PEM, ironically it’s more an issue with mental exertion. In context ↗
  • Anxiety & low moodmy anxiety has been out of control (and related panic attacks 📈📈) In context ↗
  • Gut problemsI’m now experiencing some sort of chronic anal fissure or potentially infection In context ↗

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