About a year into long COVID with terrible fatigue, no improvement from routines or Zoloft
- Condition
- Long COVID
- At worst
- Moderate (mostly housebound)
- Ill for
- 18 months
- Last post
- Feb 2026
In their words
- At worst: Moderate
my mom who took care of so many of the basic living functioning things
In context ↗ - Now: No benefit
I know I’ve regressed
In context ↗ - Began after: a vaccination
my theory that my vax injury is more taking the path of creating havoc in my body from an immune response standpoint
- Says they never had: Breathlessness
I don’t have chronic pain or *knock on wood* heart related symptoms like being out of breath for the simplest things.
- Says they never had: Heart symptoms & palpitations
I don’t have chronic pain or *knock on wood* heart related symptoms like being out of breath for the simplest things.
- Says they never had: Pain & fibromyalgia
I don’t have chronic pain
Read from 5 of their posts and comments; links to the 4 this page draws on
Summary
A Reddit user with long COVID who attributed their illness to a vaccine injury was about a year in when they posted in late 2025, with terrible fatigue and, later, worsening anxiety but no chronic pain and no physical PEM they were aware of. They spent four months at the lake with their mother being cared for, then regressed after returning home. Habit routines gave them a rested feeling and restarting Zoloft slightly eased their anxiety.
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What they tried
Also tried
Their words about each treatment
- herbal tincture for EBV · No change
some tincture they ordered me that’s herbal made specifically for EBV ... I don’t think it’s done anything to help
In context ↗ - vitamin d/k · Not said
I’m on a few other basic immune system stuff and vitamin d/k
In context ↗ - slowing down / not fighting it · Worse
I honestly think I’m worse once I found out about the reactivated EBV because I forced myself to slow down and not fight it
In context ↗ - daily routine and habits · Helped
the habits became things that weren’t decisions or choices my brain was making about what’s next ... that gave me ao much of a rested feeling that I never expected
In context ↗ - verilux happy light · Helped
putting my verilux happy light on for 30 minutes while eating ... that gave me ao much of a rested feeling that I never expected
In context ↗ - ivermectin · No change
My doctor didn’t prescribe any medication other than a too low dose of ivermectin ... I don’t think the ivermectin or the entire “treatment” plan he put me on
In context ↗ - Zoloft · Helped
ive noticed a difference already albeit slightly
In context ↗ - another antidepressant · Not said
I have major depressive disorder - I’m on another antidepressant as well
In context ↗ - klonopin · Helped
taking my klonopin on a semi-regular basis acted like a reset button for my anxiety
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| onset | illness onset, which they call a vaccine injuryThe first thing I said out loud was over a year ago ... I don’t feel sick usually but I never feel well.In context ↗ | Moderate |
| summer 2025 | four months at the lake with their mother caring for themspending ~4 months at the lake with my mom who took care of so many of the basic living functioning things so I could truly try to healIn context ↗ | Moderate |
| autumn 2025 | returned home after the summer and regressedso I know I’ve regressed and probably can’t heal in this environmentIn context ↗ | Moderate |
| 2025-12-14 | small daily routines gave them a rested feelingthat gave me ao much of a rested feeling that I never expectedIn context ↗ | Moderate |
| 2026-02-03 | restarted Zoloft for out-of-control anxiety; slightly better, still illive noticed a difference already albeit slightlyIn context ↗ | Moderate |
Adverse events
- Sertraline (Zoloft)“I did recently forget to take my Zoloft and had a hard time getting back on it without having severe nausea symptoms.” In context ↗ Gut side effects
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
I don’t think I have a physical manifestation of PEM, ironically it’s more an issue with mental exertion.
In context ↗ - Anxiety & low mood
my anxiety has been out of control (and related panic attacks 📈📈)
In context ↗ - Gut problems
I’m now experiencing some sort of chronic anal fissure or potentially infection
In context ↗