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ME/CFS Outcome unclear

ME/CFS with usual PEM; nicotine patch caused herx-like reaction, Lief life changing

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Jul 2025
In their words
Read from 2 of their posts and comments; links to the 2 this page draws on

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Summary

Someone who describes their usual PEM tried a nicotine patch for the first time and had a distinct herx-like reaction unlike their PEM, one of only a few such reactions over the years after new medications or supplements. In 2023 they had been using a Lief biofeedback device for a little over a week and called it life changing, and were new to resonance breathing and could not vouch for the long term.

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What they tried

Also tried

Lief biofeedback app· Helped a lotresonance breathing· Helpednicotine patch· Worse
Their words about each treatment
  • resonance breathing · Helpedbreathing at that rhythm has amazing effects on HRV, both short term and longterm (well, I'm new to this, so I can't vouch for the longterm yet) In context ↗
  • Lief biofeedback app · Helped a lotI've only been using mine a little over a week and honestly it's been life changing. In context ↗
  • nicotine patch · Worsethat is just what I experienced after trying nicotine patch for the first time In context ↗

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happenedAfter
2023-08-07began resonance breathing guided by Lief biofeedback for HRVI've only been using mine a little over a week and honestly it's been life changing. In context ↗
—herx-like reaction after first nicotine patchthat is just what I experienced after trying nicotine patch for the first time In context ↗Nicotine patches
2025-07-17still having usual PEMthey feel different than my usual PEM In context ↗

Adverse events

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaisethey feel different than my usual PEM In context ↗

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