ME/CFS flaring above 3,300 steps a day, somewhat better after hydroxycobalamin injection
- Condition
- ME/CFS
- At worst
- Mild (working or studying, with limits)
- Ill before improving or writing
- Not stated
- Last post
- Nov 2025
In their words
- Condition: ME/CFS
Cipro triggered my ME.
In context ↗ - At worst: Mild
i was averaging around 3300 steps per day and now a week after injection I seem to be able to take 3800 per day and not flare from it (which I would’ve before)
In context ↗ - Now: Somewhat better
The improvement is not life changing but it’s definitely noticeable and the best supplement/treatment success I have had.
In context ↗
Read from 9 of their posts and comments; links to the 7 this page draws on
Summary
After Cipro triggered their ME, Pond 30752 was averaging about 3,300 steps a day and would flare from more. A 1500 mcg hydroxycobalamin injection in January 2025 raised that to about 3,800 steps without flaring - a small but noticeable gain they call their best treatment result. Similar injections years earlier had helped 10-20% before fading, so they stopped. They also take low-dose bisoprolol, which mostly keeps them under the POTS threshold.
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What they tried
What they credit
Also tried
Their words about each treatment
- Hydroxycobalamine subq injections · Helped
I’m noticing that it improved my baseline a little bit
In context ↗ - B12 tablets · No change
I don’t notice anything from tablets even at a higher dose.
In context ↗ - Electrolytes · Helped
Noticed mine has been a lot lower during the day and when standing since taking one portion of electrolytes with a lot of water every morning.
In context ↗ - Bisoprolol · Helped
I take low dose Biso and it is enough to mostly keep me under the POTS threshold
In context ↗ - Sitting in a blow up pool · Helped
when I’m sitting in it it makes me feel so much better ... that good feeling tends to stick around a little even when I get out again
In context ↗ - Pacing by step counting · Not said
Counting steps is the most important part for pacing myself.
In context ↗
Approaches: Supplements
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 2 steps say too little to place on the scale and are only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| onset | ME triggered by a course of CiproCipro triggered my ME.In context ↗ | Not stated | |
| 2024-10-19 | baseline before B12, flaring from activityi was averaging around 3300 steps per dayIn context ↗ | Mild | |
| years ago | 10-20% improvement from B12 injections that later fadedI improved by 10-20% from those injections but I felt like the effects weakened over time so eventually I stoppedIn context ↗ | Not stated | Vitamin B12 |
| 2025-01-13 | higher step count without flaring after hydroxycobalamin injectioni was averaging around 3300 steps per day and now a week after injection I seem to be able to take 3800 per day and not flare from itIn context ↗ | Mild | Vitamin B12 |
| 2025-11-14 | POTS mostly kept in check with low-dose bisoprololI take low dose Biso and it is enough to mostly keep me under the POTS thresholdIn context ↗ | Mild |
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
not flare from it (which I would’ve before)
In context ↗ - POTS & dysautonomia
I take low dose Biso and it is enough to mostly keep me under the POTS threshold
In context ↗
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