Long COVID
Mild → somewhat betterIll 2 months before improving or writing
Long COVID insomnia, 3-4 hours sleep, somewhat better with amitriptyline and Zoloft
- Condition
- Long COVID
- At worst
- Mild (working or studying, with limits)
- Ill before improving or writing
- 2 months
- Last post
- Mar 2025
In their words
- Condition: Long COVID
Came home from vacation in January. Started getting panic attacks from my thc. Tested positive and almost have all the same symptoms.
In context ↗ - At worst: Mild
I think I’d be back to almost at least 90% if I could sleep.
In context ↗ - Now: Somewhat better
I’m not sure yet how much it’s helping me, and it’s been about a month now, but I do feel a bit better as far as anxiety and depression goes.
In context ↗ - Began after: COVID
Came home from vacation in January. Started getting panic attacks from my thc. Tested positive and almost have all the same symptoms.
In context ↗
Read from 21 of their posts and comments; links to the 7 this page draws on
Summary
A Reddit user who developed long COVID in January 2025, with intractable insomnia as the main problem: about three to four hours of poor sleep a night. Hydroxyzine, trazodone, Ambien, Seroquel, melatonin, magnesium and THC edibles all failed to restore sleep. Amitriptyline helped slightly and Zoloft eased anxiety and depression after about a month. They said they would be near 90% if they could sleep.
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What they tried
Also tried
Hydroxyzine· HelpedZoloft· HelpedAmitriptyline· HelpedAmbien· No changeTHC/cannabis (indica gummies)· No changeSeroquel· No changeMelatonin· No changeMentally counting· No changeTrazadone· WorseCBD· Not saidMagnesium glycinate· Not saidUnisom· Not said
Their words about each treatment
- Hydroxyzine · Helped
Hydroxyzine(50 mg gets me about 3 hours of sleep)
In context ↗ - Ambien · No change
Ambien ( 10 mg made me sleep for like 3 hours)
In context ↗ - Trazadone · Worse
Trazadone (100 mg made my heart race and head spin)
In context ↗ - CBD · Not said
I’ve already tried hydroxyzine, ambien, trazadone, cbd.
In context ↗ - THC/cannabis (indica gummies) · No change
I’ve tried so many different indica gummies now and they used to knock me out. Now they don’t.
In context ↗ - Magnesium glycinate · Not said
Magnesium glycinate ( I take 360 mg a day)
In context ↗ - Zoloft · Helped
I do feel a bit better as far as anxiety and depression goes
In context ↗ - Seroquel · No change
Seroquel (50 mg made me tired but wired)
In context ↗ - Melatonin · No change
Last night I mixed it with melatonin and that did pretty much nothing.
In context ↗ - Amitriptyline · Helped
the only one that seems to be helping a small bit is amitriptyline
In context ↗ - Unisom · Not said
I also sometimes use thc/con edibles and unisom.
In context ↗ - Mentally counting · No change
Okay well I got to about 270 and felt crazy like why am I not asleep yet?!
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| January 2025 | Long COVID after a positive test following a vacation; panic attacks and then insomnia beganCame home from vacation in January. Started getting panic attacks from my thc. Tested positive and almost have all the same symptoms.In context ↗ | Mild |
| March 2025 | insomnia at its worst, letting it eat them alive, depressedI spent last week letting the insomnia eat me alive.In context ↗ | Mild |
| 2025-03-25 | amitriptyline giving slight sleep help; Zoloft easing anxiety and depression after about a monthI do feel a bit better as far as anxiety and depression goes.In context ↗ | Mild |
Adverse events
- Quetiapine (Seroquel)“Seroquel (50 mg made me tired but wired)” In context ↗ Side effects
- Melatonin“Honestly I feel like melatonin makes me more awake.” In context ↗ Insomnia from treatment
- Trazodone (Desyrel)“Trazadone (100 mg made my heart race and head spin)” In context ↗ Heart rhythm problems
Symptoms mentioned
Their words about their symptoms
- Sleep problems
I feel like I get about 3-4 hours of okay sleep and the rest is just trash.
In context ↗ - Anxiety & low mood
due to the insomnia I became very depressed
In context ↗