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ME/CFS Outcome unclear

ME/CFS: many antidepressants tried, then immediate-release bupropion over several years

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Mar 2026
Read from 1 of their posts and comments; links to the one this page draws on

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Summary

Posting in an ME/CFS forum, this person reported "really amazing results" from immediate-release bupropion taken over several years, after trying a lot of other antidepressants, and called it unique among antidepressants and probably safer than dextromethorphan. Beyond that, their own illness, its severity and its course are not described.

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What they tried

Their words about each treatment
  • immediate release bupropion · Helped a lotI had really amazing results with the immediate release bupropion over the years In context ↗
  • a lot of different ones · Not saidI did try a lot of different ones In context ↗

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