ME/CFS for 30 years made work a struggle, now energetic with Zyrtec and Pepcid
- Condition
- ME/CFS
- At worst
- Mild (working or studying, with limits)
- Ill before improving or writing
- 30 years
- Last post
- Apr 2026
In their words
- Condition: ME/CFS
I went from struggling to work full time to downright energetic after about 30 some odd years
In context ↗ - At worst: Mild
struggling to work full time
In context ↗ - Now: Recovered
downright energetic
In context ↗
Read from 1 of their posts and comments; links to the one this page draws on
Summary
After about 30 years of fatigue that left them struggling to work full time, they took Zyrtec and Pepcid four times a day and said it finally worked after trying everything, leaving them "downright energetic". A specialist they saw for hypermobile Ehlers-Danlos syndrome said the response was solid evidence of mast cell activation syndrome.
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What they tried
What they credit
Their words about each treatment
- Zyrtec · Helped a lot
by taking Zyrtec and Pepcid 4 times a day. I had tried absolutely everything and that finally did it.
In context ↗
Approaches: H1 antihistamines · H2 blockers
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| onset | chronic fatigue; still working full time with difficultyI went from struggling to work full timeIn context ↗ | Mild | |
| 2026-04-02 | became energetic after Zyrtec and Pepcid four times a dayI went from struggling to work full time to downright energetic after about 30 some odd years by taking Zyrtec and Pepcid 4 times a day.In context ↗ | Recovered | Cetirizine (Zyrtec) |
Symptoms mentioned
Their words about their symptoms
- Mast cell (MCAS) & allergies
she said that was pretty solid evidence for mast cell activation syndrome
In context ↗
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