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Long COVID Mild → no benefit

Long COVID, completely not functional after a Wellbutrin dose, still no improvement

Condition
Long COVID
At worst
Mild (working or studying, with limits)
Ill for
Not stated
Last post
Mar 2026
In their words
  • Condition: Long COVIDhttps://www.reddit.com/r/LongCovid/comments/1qmz0in/_/o1sn3o5/ In context ↗
  • At worst: MildThankfully I work in the department right next to the ER and my co workers were able to convince me to check in In context ↗
  • Now: No benefitI am on week 2 of injections and it is definitely worse but I wasn't in a great place starting out either In context ↗
Read from 3 of their posts and comments; links to the 3 this page draws on

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Summary

In March 2024 they reported that a single dose of Wellbutrin left them completely not functional and led to an ER visit. In January 2026 they were two weeks into an unnamed trial of injections and felt definitely worse, after a few scary symptoms the week before that they linked to neuroinflammation. By March 2026 they were mixing citric acid with salt to meet intake goals.

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What they tried

Also tried

Their words about each treatment
  • wellbutrin · Much worseI tried wellbutrin once. Ended up in the ER 8 hours later completely not functional almost black out drunk reaction. In context ↗
  • injections · WorseI am on week 2 of injections and it is definitely worse In context ↗
  • salt · Not saidI played around with citric acid ratios so I could meet the intake goals without gagging from the flavor In context ↗

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happened
2024-03-08one dose of Wellbutrin left them completely not functional and sent them to the ERI tried wellbutrin once. Ended up in the ER 8 hours later completely not functional In context ↗
2026-01-26two weeks into trial injections, worse, with a few scary symptomsI am on week 2 of injections and it is definitely worse but I wasn't in a great place starting out either. In context ↗
2026-03-08mixing citric acid with salt to meet electrolyte intake goalsso I could meet the intake goals without gagging from the flavor In context ↗

Adverse events

  • Bupropion (Wellbutrin)“I tried wellbutrin once. Ended up in the ER 8 hours later completely not functional almost black out drunk reaction.” In context ↗ ER visit
  • Bupropion (Wellbutrin)“Ended up in the ER 8 hours later completely not functional almost black out drunk reaction.” In context ↗ Side effects
  • “I am on week 2 of injections and it is definitely worse but I wasn't in a great place starting out either.” In context ↗ Made symptoms worse
  • “Had a few weird scary symptoms last week that line up with the drug having some sort of effect on neuroinflamation.” In context ↗ Side effects

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