Long COVID with reactivated EBV much better after tenofovir
- Condition
- Long COVID
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- Jul 2025
In their words
- Condition: Long COVID
EBV reactivation from Long Covid
In context ↗ - Now: Much better
it was a game changer! Finally got me to negative and made a massive different.
In context ↗ - Began after: COVID
EBV reactivation from Long Covid
In context ↗
Read from 1 of their posts and comments; links to the one this page draws on
Summary
A person with long COVID and reactivated EBV was first treated with Valtrex. It caused mild side effects, which they adapted to, and helped quite a bit, but stopped being effective after about six months. Their doctor switched them to tenofovir, which produced a major improvement and brought the EBV to negative. They still take L-lysine as needed when a flare starts.
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What they tried
What they credit
Also tried
Their words about each treatment
- Valtrex · Helped
My doctor first put me on Valtrex for EBV reactivation from Long Covid. I had some mild side effects, but adapted and it helped quite a bit. However it stopped being effective for me after about 6 months
In context ↗ - Tenofovir · Helped a lot
He switched me to Tenofovir and it was a game changer! Finally got me to negative and made a massive different.
In context ↗ - L-Lysine · Helped
I still take L-Lysine as needed when I start to feel a flare.
In context ↗
Approaches: Antivirals
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | Long COVID with EBV reactivationEBV reactivation from Long CovidIn context ↗ | |
| — | Valtrex helped quite a bitit helped quite a bitIn context ↗ | Valtrex / valacyclovir |
| — | Valtrex stopped being effective after about 6 monthsit stopped being effective for me after about 6 monthsIn context ↗ | |
| — | Tenofovir produced a major improvement and brought EBV to negativeFinally got me to negative and made a massive different.In context ↗ | Tenofovir (Viread, Vemlidy) |
| 2025-07-03 | Still taking L-lysine as needed for flaresI still take L-Lysine as needed when I start to feel a flare.In context ↗ |
Adverse events
- Valtrex / valacyclovir“I had some mild side effects, but adapted and it helped quite a bit.” In context ↗ Side effects
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