ME/CFS
Somewhat better
Intolerant to everything with ME/CFS, somewhat better after antihistamine microdosing
- Condition
- ME/CFS
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- Jul 2025
In their words
- Condition: ME/CFS
At my worst I couldn’t handle anything either. My throat would tighten to absolutely everything including a single drop of Cromolyn of any kind.
In context ↗ - Now: Somewhat better
I very slowly was able to titrate it up to a full dose.
In context ↗
Summary
Lake 82235 wrote that at their worst they could not tolerate anything, with their throat tightening to everything including a single drop of Cromolyn. They began microdosing an antihistamine from a barely visible speck and slowly titrated to a full dose. It took a year to find a workable microdose and several months to get fully onto supplements, including magnesium and vitamin C, and compounded Cromolyn.
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What they tried
Also tried
Their words about each treatment
- Allegra · Helped
I very slowly was able to titrate it up to a full dose.
In context ↗ - Cromolyn sodium · Helped
I also used the mast cell stabilizer Cromolyn sodium.
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | At worst could not tolerate any medication; throat tightened to everythingAt my worst I couldn’t handle anything either. My throat would tighten to absolutely everything including a single drop of Cromolyn of any kind.In context ↗ | |
| 2025-07-16 | Slowly titrated from a speck of antihistamine to a full dose and got fully onto supplementsIt took me a year to finally figure out I could microdose at such a low level and then several months to get fully on supplements.In context ↗ | Fexofenadine (Allegra) |
Adverse events
- Fexofenadine (Allegra)“I started with an antihistamine ... It still made my throat extremely tight.” In context ↗ Allergic reaction / anaphylaxis
- Cromolyn (Gastrocrom, Nalcrom)“My throat would tighten to absolutely everything including a single drop of Cromolyn of any kind.” In context ↗ Allergic reaction / anaphylaxis
Symptoms mentioned
Their words about their symptoms
- Mast cell (MCAS) & allergies
I just knew I had to get the supplements in to calm my mast cells down so I was persistent.
In context ↗