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ME/CFS Outcome unclear

Very severe insomnia in ME/CFS; several medications helped no more than two days

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Oct 2026
Read from 1 of their posts and comments; links to the one this page draws on

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Summary

A Reddit user in r/cfs reported very severe insomnia and hyperadrenergic orthostatic intolerance. They had tried mirtazapine, quetiapine, Divalgin and trazodone, but none of these medications helped for more than two days, and they were terrified of not being able to fall asleep again.

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What they tried

Their words about each treatment
  • mirtazapine · HelpedI’ve tried mirtazapine, quetiapine, Divalgin, and trazodone. But, unfortunately, none of these medications helped for more than two days. In context ↗

Symptoms mentioned

Their words about their symptoms
  • Sleep problemsI have very severe insomnia. In context ↗
  • POTS & dysautonomiaI also have orthostatic intolerance of the hyperadrenergic type. In context ↗

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