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ME/CFS Outcome unclearNeeds ongoing treatment

ME/CFS: PEM raised histamine, dry cough and digestive issues; quercetin and fexofenadine

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Jul 2025
In their words
  • Condition: ME/CFSMore PEM > more histamine > more digestive tract problems In context ↗
Read from 2 of their posts and comments; links to the 2 this page draws on

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Summary

Reported post-exertional malaise that raised histamine and led to a dry cough followed by digestive problems. They took quercetin daily for prevention and fexofenadine when PEM hit. Since starting antihistamines, at the latest when the cough appeared, they no longer had digestive problems.

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What they tried

Their words about each treatment
  • quercetin · Not saidFor prevention, I take quercetin daily In context ↗
  • fexofenadine · Helpedsince I started taking antihistamines (at the latest when I cough), I no longer have digestive problems In context ↗

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaisefor PEM, I also take fexofenadine In context ↗
  • Gut problemsbut since I started taking antihistamines (at the latest when I cough), I no longer have digestive problems In context ↗
  • Mast cell (MCAS) & allergiesIf my histamine is high, I first get a dry cough In context ↗

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