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ME/CFS Outcome unclear

ME/CFS with noise and conversation intolerance; THC, ibuprofen and dextromethorphan tried

Condition
ME/CFS
At worst
Not stated
Ill for
Not stated
Last post
Aug 2026
In their words
  • Condition: ME/CFSIt doesnt prevent PEM but it helps it be less severe. In context ↗
Read from 3 of their posts and comments; links to the 3 this page draws on

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Summary

A person with ME/CFS who could not tolerate prolonged noise or conversation found low-dose THC gummies (about 0.5 mg) alleviated sensory sensitivity; ibuprofen helped a little. Dextromethorphan did not prevent PEM but made it less severe, and THC had a similar effect. In August 2026 they reported that L-phenylalanine made a noticeable difference.

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What they tried

Their words about each treatment
  • ibuprofen · HelpedSometimes ibuprofen helps a little bit In context ↗
  • thc gummies · Helpedthe only thing that lets me tolerate any kind of prolonged noise (videos, conversations, etc) are thc gummies. I take a really low dose, like .5 mg In context ↗
  • Dextromethorphan · HelpedDextromethorphan has helped me some. It doesnt prevent PEM but it helps it be less severe. In context ↗
  • L-phenylanaline · HelpedL-phenylanaline made a noticeable difference for me! In context ↗

Symptoms mentioned

Their words about their symptoms
  • Light & noise sensitivityit really helps alleviate sensory sensitivity In context ↗
  • Post-exertional malaiseIt doesnt prevent PEM but it helps it be less severe In context ↗

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