ME/CFS
No benefitIll for 9 years
Vision dark on standing after spironolactone; orthostatic symptoms persist with ME/CFS
- Condition
- ME/CFS
- At worst
- Not stated
- Ill for
- 9 years
- Last post
- Sep 2026
In their words
- Condition: ME/CFS
Now I’m diagnosed POTS and ME too.
In context ↗ - Now: No benefit
Quit after 3 months but the orthostatic stuff never fully bounced back.
In context ↗
Read from 1 of their posts and comments; links to the one this page draws on
Summary
Crest 52452 started spironolactone around 2017 for hormonal acne and within two weeks was a zombie, unable to stand without their vision going dark and waking with a choking dry mouth. They quit after three months, but the orthostatic symptoms never fully resolved, and they were later diagnosed with POTS and ME. They suspected the drug flipped a switch, though doctors called lingering effects unlikely.
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What they tried
Also tried
Their words about each treatment
- spironolactone · Worse
Started it around 2017 for hormonal acne and within two weeks I was a zombie, couldn’t stand without my vision going dark, mouth so dry I’d wake up choking. Quit after 3 months but the orthostatic stuff never fully bounced back.
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | Where they were |
|---|---|---|
| 2017 | started spironolactone for hormonal acne; symptoms beganStarted it around 2017 for hormonal acne and within two weeks I was a zombieIn context ↗ | Not stated |
| 2017 | a zombie, could not stand without vision going dark, dry mouth waking them chokingwithin two weeks I was a zombie, couldn’t stand without my vision going dark, mouth so dry I’d wake up chokingIn context ↗ | Severe |
| 2017 | quit spironolactone; orthostatic symptoms never fully bounced backQuit after 3 months but the orthostatic stuff never fully bounced back.In context ↗ | Not stated |
| 2026-09-03 | diagnosed with POTS and ME; orthostatic symptoms persistNow I’m diagnosed POTS and ME too.In context ↗ | Not stated |
Adverse events
- Spironolactone“within two weeks I was a zombie ... mouth so dry I’d wake up choking” In context ↗ Side effects
- Spironolactone“couldn’t stand without my vision going dark” In context ↗ Low blood pressure or fainting
- Spironolactone“Quit after 3 months but the orthostatic stuff never fully bounced back.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- POTS & dysautonomia
couldn’t stand without my vision going dark ... the orthostatic stuff never fully bounced back
In context ↗