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ME/CFS Mild → no benefit

Constant tiredness with ME/CFS, still exhausted despite thyroid medication

Condition
ME/CFS
At worst
Mild (working or studying, with limits)
Ill for
Not stated
Last post
Jul 2026
In their words
  • Condition: ME/CFSI'm currently seeing an endocrinologist for my persistent chronic fatigue issues. In context ↗
  • At worst: MildI can't increase my exercise routine as I am already exhausted from everything I currently do and my physically stressful job. In context ↗
  • Now: No benefitI'm hypothyroid and medicated but still constantly tired. In context ↗
Read from 2 of their posts and comments; links to the 2 this page draws on

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Summary

A Reddit user with persistent chronic fatigue and treated hypothyroidism reported constant tiredness despite medication. They had lost 70 lbs through diet and exercise but gained 25 lbs over six months after a medication change. They were considering GLP-1 drugs with an endocrinologist and had not started them; they remained exhausted by their physically stressful job.

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What they tried

Also tried

medicated· Not saidimprovement of diet· Not saidexercise· Not said
Their words about each treatment
  • medicated · Not saidI'm hypothyroid and medicated but still constantly tired. In context ↗
  • improvement of diet · Not saidI lost 70lbs with improvement of diet and exercise In context ↗
  • exercise · Not saidmy initial weight loss was from me literally eating and exercising with bodybuilder level discipline In context ↗

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happenedWhere they were
—Persistent chronic fatigue with treated hypothyroidismI'm currently seeing an endocrinologist for my persistent chronic fatigue issues. I'm hypothyroid and medicated but still constantly tired. In context ↗Not stated
2026-07-10Still exhausted by work and exercise; considering GLP-1I can't increase my exercise routine as I am already exhausted from everything I currently do and my physically stressful job. In context ↗Mild

Adverse events

  • “the last 6 months I unexpectedly gained 25lbs after a medication change” In context ↗ Side effects

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