How it went
Did it last?
- 2 of 12 said the benefit wore off (including the 1 who relapsed).
- No one said they needed to keep it up to stay well.
Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.
| Outcome described | Accounts | Share |
|---|---|---|
| Full recovery | 1 | 8% |
| Near-full | 0 | 0% |
| Substantial | 4 | 33% |
| Partial | 4 | 33% |
| Relapsed | 1 | 8% |
| No benefit | 2 | 17% |
By how ill people were
| Severity at worst | How it went | n | Recovered |
|---|---|---|---|
| Moderate | 4 | 0% | |
| Severe | 3 | 33% |
5 accounts don’t say how ill the person was.
Who published these accounts
Right-hand number: share describing a full or near-full recovery. Pages that sell something, and advocacy sites, tend to publish only the successes.
How often it comes up
Posts that mention Nattokinase and fibrinolytics, per 1,000 posts each year. Hover a point for the count.
Show as a table
| Year | Posts mentioning it | All posts | Per 1,000 |
|---|---|---|---|
| 2009 | 0 | 184 | 0.0 |
| 2010 | 0 | 682 | 0.0 |
| 2011 | 0 | 704 | 0.0 |
| 2012 | 4 | 1,491 | 2.7 |
| 2013 | 2 | 1,708 | 1.2 |
| 2014 | 1 | 2,352 | 0.4 |
| 2015 | 5 | 2,158 | 2.3 |
| 2016 | 6 | 1,431 | 4.2 |
| 2017 | 9 | 3,110 | 2.9 |
| 2018 | 0 | 2,201 | 0.0 |
| 2019 | 0 | 1,075 | 0.0 |
| 2020 | 2 | 2,581 | 0.8 |
| 2021 | 0 | 1,867 | 0.0 |
| 2022 | 7 | 1,166 | 6.0 |
| 2023 | 3 | 1,000 | 3.0 |
| 2024 | 2 | 1,237 | 1.6 |
| 2025 | 9 | 1,019 | 8.8 |
| 2026 (so far) | 0 | 840 | 0.0 |
Posts in the forum threads we archived, 26,806 in all, counted per year. A mention means the post names the treatment, not that the writer took it. These threads all contain a recovery story, so they show what those communities discussed, not everyone with ME/CFS or long COVID. All trends
All 12 accounts
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Blood and circulation
Tried a combination of nattokinase, turmeric and bromelain for ME/CFS-related circulation problems. Had orthostatic intolerance, weakness and poor circulation beforehand. While taking the combination felt good with no orthostatic intolerance or weakness, and…
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Blood and circulation
Tried a nattokinase and serrapeptase blend for ME/CFS-related circulation concerns for about three weeks. Illness duration and severity are not detailed. Decided to discontinue after noticing an unexpected bruise on one of her palms, reporting no benefit…
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Is electro-magnetic field (EMF) hypersensitivity a real thing?
Electromagnetic avoidance was practiced through device substitution, an e-ink e-reader with wireless disabled, and shielding with anti-EMF fabric around a computer tower, combined with enzyme supplements serrapeptase and papain and later a product called…
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Ten Months of Long COVID
Marie Sanchez Nelson describes taking cetirizine, an antihistamine that calms her nervous system "in minutes," and had started nattokinase just three days before this post, which she hypothesizes may help repair blood vessels; no doses or durations are given…
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Daughter's recovery details
The regimen for Celandine's daughter included daily liquorice root powder and salt in plant milk, weekly-then-tapering Perrin Technique osteopathy (including breast lymphatic massage), the POTS medications ivabradine and midodrine with salt tablets and 2…
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Impact of extended-course Paxlovid in established Long COVID (Case 2)
Case 2, a 45-year-old woman about 11 months into Long COVID with orthostatic intolerance, tachycardia, short-term memory loss, word-finding trouble, fatigue, PEM and MCAS symptoms, took a 15-day extended course of Paxlovid (nirmatrelvir/ritonavir) in…
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Microclot results in ME
Lumbrokinase, dose and duration unspecified, was described by an ME/CFS forum member as the best among the fibrinolytic microclot-targeting enzymes they had tried, ahead of alternatives like nattokinase and bromelain. No illness duration, severity, or…
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Serrapeptase gives me more energy and no brain fog, why?
One capsule of 40,000 SPU serrapeptase before meals produced, within 4-5 hours and lasting 2-3 days, a jump in energy, sharper focus, no brain fog, reduced depression, better skin and relief from sinusitis and mold/chemical itching, according to this poster;…
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I get chills for 2 weeks after a single attempt of killing gut microbes; permanent cure found: cod liver/oil or sashimi. See last post.
After years of extreme gut-microbe intolerance triggering two-week chill/flu episodes from nattokinase, probiotics, eucalyptus oil and charcoal-based antimicrobials, she reported that ultra-dilute sauerkraut sap gave her "more good than bad effects" for the…
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My start to healing and how Tendonitis/Tendonosis/Bursitis/Gout can overlap and mimic each other
A longtime ME/CFS poster reframed two years of debilitating bilateral shoulder pain as "atypical gout" tied to a suspected nightshade/solanine sensitivity. Over 6-12+ months on a large supplement stack plus avoiding nightshades, he regained most shoulder…
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Significant improvement on Boluoke (due to sticky blood)
cigana reports significantly more energy and stamina while walking, plus resolved stomach bloating, on 6 capsules/day of the branded lumbrokinase product Boluoke, attributing it to improved blood flow to previously under-perfused tissue. He confirmed the…
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Significant improvement on Boluoke (due to sticky blood)
Replying in the same thread, Sushi describes improved blood flow after 7 months of heparin injections followed by high-dose nattokinase, without giving further specifics on degree or durability.