ME/CFS
Mild → no benefit
Lifelong fatigue with ME/CFS, no improvement from antidepressants or stimulants
- Condition
- ME/CFS
- At worst
- Mild (working or studying, with limits)
- Ill for
- lifelong
- Last post
- Dec 2025
In their words
- Condition: ME/CFS
I’ve gone to a psychiatrist who diagnosed me with generalized anxiety disorder, CFS and mild high functioning autism.
In context ↗ - At worst: Mild
Can’t find the mental energy to do much, also have cognitive problems- poor reading and auditory processing.
In context ↗ - Now: No benefit
when the endorphins rush wears off several hours later I go back to my baseline
In context ↗ - Began after: nothing they could name
I’ve had this problem for my entire life but it waxes and wains.
In context ↗ - Says they never had: Post-exertional malaise
afterward I’m either better or just as bad as when I started, never worse
Read from 10 of their posts and comments; links to the 7 this page draws on
Summary
Lifelong fatigue that waxes and wanes, with poor reading and auditory processing and mild sleep apnoea; a psychiatrist diagnosed CFS, generalised anxiety and mild high-functioning autism. Vigorous exercise briefly reduces fatigue once they push past the first 10-20 minutes, but starting is a daily struggle and the effect wears off after hours. Antidepressants and ADD stimulants didn't help, and stimulants made their heart race; they remain at baseline.
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What they tried
Also tried
Their words about each treatment
- vigorous exercise · Helped
for me it improves my energy if it’s sufficiently vigorous for enough time
In context ↗ - cpap or oral appliance · Not said
Have a lot of difficulty using cpap or oral appliance
In context ↗ - ADD medications / stimulants · Worse
Stimulants weren’t effective for me and made my heart race
In context ↗ - anti depressants · Worse
I’ve tried loads of anti depressants and they didn’t help. They made me unmotivated and tired
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| — | Lifelong fatigue that waxes and wanesI’ve had this problem for my entire life but it waxes and wains.In context ↗ | Mild |
| 2025-12-03 | Still at baseline; hard to start exercise, which briefly helpsYeah, when the endorphins rush wears off several hours later I go back to my baseline.In context ↗ | Mild |
Adverse events
- Antidepressants (unspecified)“They made me unmotivated and tired but it felt different than the fatigue I normally experience.” In context ↗ Mood or psychiatric effects
- Stimulants (unspecified)“Stimulants weren’t effective for me and made my heart race.” In context ↗ Heart rhythm problems
Symptoms mentioned
Their words about their symptoms
- Brain fog
also have cognitive problems- poor reading and auditory processing
In context ↗ - Sleep problems
If I don’t get perfect sleep it’s even harder.
In context ↗ - Anxiety & low mood
a psychiatrist who diagnosed me with generalized anxiety disorder, CFS and mild high functioning autism
In context ↗