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ME/CFS Severe → somewhat better

Bedridden with ME/CFS and depressed, now somewhat better with Wellbutrin and Effexor

Condition
ME/CFS
At worst
Severe (mostly bedbound)
Ill before improving or writing
Not stated
Last post
Jul 2026
In their words
  • Condition: ME/CFSmy CFS is really bad In context ↗
  • At worst: SevereI was basically bed ridden In context ↗
  • Now: Somewhat betterit helps, but if the CFS ever becomes more moderate, quitting the drugs may be difficult In context ↗
Read from 1 of their posts and comments; links to the one this page draws on

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Summary

Fox 74124 describes having CFS that is really bad, having been basically bedridden, too depressed and losing muscle mass after holding off medication as long as possible. A psychiatrist prescribed Wellbutrin and Effexor, and they say the drugs help. They expect quitting the drugs may be difficult if the CFS ever becomes more moderate, and they were still trying to work out a circadian rhythm approach.

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What they tried

Their words about each treatment
  • Wellbutrin · HelpedPsychiatrist prescribed Wellbutrin and Effexor ... it helps, but if the CFS ever becomes more moderate, quitting the drugs may be difficult In context ↗

Approaches: SNRIs · Other antidepressants

Their path

Very severeSevereModerateMildNear normalRecovered

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.

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WhenWhat happenedWhere they were
—bedridden before medication, losing muscle massI held off as long as I could, but I was basically bed ridden. ... I was losing too much muscle mass. In context ↗Severe
—started prescribed antidepressants, some helpPsychiatrist prescribed Wellbutrin and Effexor ... it helps In context ↗Severe
2026-07-15still bad CFS, expects to stay on the drugsmy CFS is really bad ... if the CFS ever becomes more moderate, quitting the drugs may be difficult In context ↗Severe

Symptoms mentioned

Their words about their symptoms

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Asking aboutFox 74124’s story

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