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ME/CFS Somewhat betterNeeds ongoing treatment

ME/CFS PEM lasting days, somewhat better with more protein and NAC

Condition
ME/CFS
At worst
Not stated
Ill before improving or writing
Not stated
Last post
Oct 2025
In their words
  • Condition: ME/CFSMy PEM went way down when I started. In context ↗
  • Now: Somewhat betterMy PEM went way down when I started. I used to get PEM that lasted days and days but now it usually lasts just a couple days. In context ↗
Read from 2 of their posts and comments; links to the 2 this page draws on

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Summary

A person with ME/CFS whose post-exertional malaise used to last days at a time said that eating more protein and taking NAC brought their PEM down a lot, so it now usually lasts only a couple of days. They built up NAC slowly to 1800-2400 mg because of nausea, taking it with food, and reported no side effects later. They still have to pace, but the consequences of overdoing it are less severe.

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Asking aboutMaple 80929’s story

What they tried

Their words about each treatment
  • NAC · HelpedMy PEM went way down when I started. I used to get PEM that lasted days and days but now it usually lasts just a couple days. In context ↗
  • Eating more protein · HelpedEating more protein and NAC help my PEM. In context ↗

Approaches: Diet · Supplements

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happened
—PEM lasting days at a timeI used to get PEM that lasted days and days In context ↗
2025-10PEM shortened to a couple of days; still has to paceMy PEM went way down when I started ... now it usually lasts just a couple days In context ↗

Adverse events

  • NAC (N-acetylcysteine)“I had to start slowly because I was getting random nausea. I’m not actually sure if it was the NAC that caused the nausea” In context ↗ Gut side effects

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaiseI still need to pace but the consequences when I don’t pace well are not as severe In context ↗
  • Gut problemsI had to start slowly because I was getting random nausea In context ↗

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Asking aboutMaple 80929’s story

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