ME/CFS
Mild → no benefit
Constant fatigue with ME/CFS; B12 and amitriptyline taper brought no improvement
- Condition
- ME/CFS
- At worst
- Mild (working or studying, with limits)
- Ill for
- several months
- Last post
- Feb 2020
In their words
- Condition: ME/CFS
Constant fatigue is a recent problem.
In context ↗ - At worst: Mild
Now that I'm working full time, things have been much harder.
In context ↗ - Now: No benefit
I do have a better mental focus, but I'm not sure it's done much of anything for tiredness.
In context ↗ - Began after: nothing they could name
It's possible I've had these symptoms for a while and just didn't notice
Read from 4 of their posts and comments; links to the 4 this page draws on
Summary
Alder 17115 had constant fatigue for several months, waking unrested, nodding off at work and wanting to go back to bed, while working full time. Labs found low B12; four months of supplements raised levels and improved mental focus but did little for tiredness. A neurologist advised tapering their long-standing 100 mg amitriptyline, taken for headaches. On day two of 75 mg they felt amazing for a day, then groggy again.
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What they tried
Their words about each treatment
- amitriptyline · Worse
Amitriptyline is known to have a sedative effect. ... my doctor believes this drug to be the culprit
In context ↗ - nortriptyline · Worse
I had issues with it. Don't remember what, it's been years.
In context ↗ - B12 supplements · Helped
I do have a better mental focus, but I'm not sure it's done much of anything for tiredness.
In context ↗ - Viibryd · Helped
It did help, but I couldn't stand the side effects, and I have since come off it.
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| several months before February 2020 | constant fatigue beganConstant fatigue is a recent problem.In context ↗ | Mild |
| before February 2020 | moved to full-time work, which made things much harderNow that I'm working full time, things have been much harder.In context ↗ | Mild |
| 2020-02-22 | still exhausted while tapering amitriptyline; one good day then groggy againI felt amazing yesterday but I'm back to feel groggy today.In context ↗ | Mild |
Adverse events
- Amitriptyline (Elavil)“For the past several months I've been absolutely exhausted. I wake up feeling completely unrested, I have nodded off at work, and I come home just wanting to go back to bed.” In context ↗ Side effects
- Vilazodone (Viibryd)“It did help, but I couldn't stand the side effects, and I have since come off it.” In context ↗ Side effects
- Nortriptyline (Pamelor)“I remember they started me on nortriptyline first, but I had issues with it.” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Sleep problems
I wake up feeling completely unrested
In context ↗ - Headaches & migraine
I take 100mg amitriptyline daily for headaches.
In context ↗ - Brain fog
I do have a better mental focus, but I'm not sure it's done much of anything for tiredness.
In context ↗