Long COVID
Relapsed
Long COVID POTS-type symptoms and brain fog improving, then worse after duloxetine
- Condition
- Long COVID
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- Mar 2025
In their words
- Condition: Long COVID
I’ve been on tirz and didn’t notice a difference in brain fog
In context ↗ - Now: Relapsed
I had tachy/POTS symptoms that were healing over the years and three weeks of Duloxetine made me worse than ever
In context ↗
Read from 4 of their posts and comments; links to the 4 this page draws on
Summary
A Reddit user in a long-COVID forum described POTS-type symptoms that had been healing over the years, plus brain fog. Tirzepatide made no difference to the brain fog. Three weeks of duloxetine (Cymbalta) made them worse than ever, with tachycardia and palpitations lasting months, and nortriptyline had a similar effect. No details of daily function were given.
Ask Miruvor AI
What they tried
Their words about each treatment
- tirz · No change
I’ve been on tirz and didn’t notice a difference in brain fog
In context ↗ - Duloxetine (Cymbalta) · Much worse
three weeks of Duloxetine made me worse than ever
In context ↗ - Nortryptiline · Worse
Nortryptiline had a similar effect in me.
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened |
|---|---|
| — | long COVID with POTS-type symptoms slowly healing over the years, and brain fogI had tachy/POTS symptoms that were healing over the yearsIn context ↗ |
| 2025-03-13 | three weeks of duloxetine made them worse than everthree weeks of Duloxetine made me worse than everIn context ↗ |
| 2025-03-13 | nortriptyline had a similar worsening effectNortryptiline had a similar effect in me.In context ↗ |
| 2025-03-28 | still ill; tachycardia and palpitations after CymbaltaCymbalta gave me tachy and palpitations for months.In context ↗ |
Adverse events
- Duloxetine (Cymbalta)“I had tachy/POTS symptoms that were healing over the years and three weeks of Duloxetine made me worse than ever.” In context ↗ Made symptoms worse
- Duloxetine (Cymbalta)“Cymbalta gave me tachy and palpitations for months.” In context ↗ Heart rhythm problems
- Nortriptyline (Pamelor)“Nortryptiline had a similar effect in me.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- POTS & dysautonomia
I had tachy/POTS symptoms that were healing over the years
In context ↗ - Brain fog
I’ve been on tirz and didn’t notice a difference in brain fog
In context ↗ - Heart symptoms & palpitations
Cymbalta gave me tachy and palpitations for months.
In context ↗