Almost bedbound with long COVID, no benefit from low-dose naltrexone or other treatments
- Condition
- Long COVID
- At worst
- Very severe (bedbound, unable to do basic care)
- Ill for
- 2.5 years
- Last post
- Sep 2025
In their words
- Condition: Long COVID
I was 26, happy, healthy, and active, but a single covid infection stole my entire life from me.
In context ↗ - At worst: Very severe
I’m now almost entirely bedbound—unable to care for myself at all.
In context ↗ - Now: No benefit
Despite trying countless treatments over the last two and a half years, nothing has meaningfully helped.
In context ↗ - Began after: COVID
a single covid infection stole my entire life from me
In context ↗
Summary
A 26-year-old became almost entirely bedbound after a COVID infection, unable to care for themselves. After two and a half years of trying countless treatments, they reported that nothing had meaningfully helped the PEM, fatigue, POTS or cognitive dysfunction. Low-dose naltrexone, slowly titrated over eight months, caused side effects with each increase and no noticeable benefit, leaving them more tired, so they stopped it.
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What they tried
Also tried
Their words about each treatment
- LDN · Worse
Tried for 8 months. Very slowly titrated up. Had side effects with each titration. No noticeable benefit, decided to stop bc it was making me MORE tired even at a lowish dose.
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. The chart starts 2.5 years after onset: the story doesn’t say how ill they were before that. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| 2022 | COVID infectiona single covid infection stole my entire life from meIn context ↗ | Not stated | |
| April 2025 | almost entirely bedbound, unable to care for selfI’m now almost entirely bedbound—unable to care for myself at all.In context ↗ | Very severe | |
| September 2025 | stopped low-dose naltrexone after no benefitNo noticeable benefit, decided to stop bc it was making me MORE tired even at a lowish dose.In context ↗ | Very severe | Low-dose naltrexone |
Adverse events
- Low-dose naltrexone“Had side effects with each titration.” In context ↗ Side effects
- Low-dose naltrexone“it was making me MORE tired even at a lowish dose.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
Nothing touches the PEM
In context ↗ - Brain fog
the cognitive dysfunction
In context ↗ - Anxiety & low mood
Feel like I’m just waiting to die
In context ↗