ME/CFS
Moderate → no benefitIll for 1 year
Year of constant nausea and limb fatigue, undiagnosed; treatments gave no improvement
- Condition
- ME/CFS
- At worst
- Moderate (mostly housebound)
- Ill for
- 1 year
- Last post
- Jun 2025
In their words
- Condition: ME/CFS
although I know that for those of us who are part of this community, this can be very difficult
In context ↗ - At worst: Moderate
I feel immense fatigue in my legs when walking short distances or for a short time, and suddenly I feel like they're going to buckle ... I have a terrible time climbing stairs and I get agitated when I do
In context ↗ - Now: No benefit
I have fear of don't have answers never and I get worse
In context ↗ - Began after: nothing they could name
A year ago, I began experiencing extreme and chronic nausea that has lasted to this day.
In context ↗ - Says they never had: Heart symptoms & palpitations
no palpitations
Summary
A 23-year-old man described a year of constant nausea along with severe fatigue in his limbs, neck and jaw, burning in his limbs, breathlessness and constipation. Endoscopy showed mild gastritis, duodenitis and Brunner's gland hyperplasia; Helicobacter pylori quadruple therapy gave no improvement and symptoms worsened on the antibiotics, while Nexium, Carafate and Cinitapride also gave no improvement. Some antiemetics, prokinetics and antacids helped only briefly. He remained undiagnosed.
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What they tried
Also tried
antiemetics· Helped · wore offprokinetic agents· Helped · wore offproton pump inhibitors· Helped · wore offantacids· Helped · wore offLexapro· Helpedtwo anti-anxiety medications· Helpedantihistamines· No changeNexium (Esomeprazole)· No changeCarafate· No changeCinitapride· No changequadruple therapy· Worse
Their words about each treatment
- antiemetics · Helped
some have helped alleviate the symptoms, they lose effectiveness a month after I start taking them
In context ↗ - Lexapro · Helped
I already take an antidepressant and two anti-anxiety medications for a mental disorder, and they've always worked well for me. ... I've been taking Lexapro for three years
- two anti-anxiety medications · Helped
I already take an antidepressant and two anti-anxiety medications for a mental disorder, and they've always worked well for me.
In context ↗ - antihistamines · No change
antihistamines, without much success
In context ↗ - quadruple therapy · Worse
He prescribed quadruple therapy for 14 days, which I completed. However, there was no improvement in my symptoms, and they even worsened.
In context ↗ - Nexium (Esomeprazole) · No change
He prescribed Nexium, Carafate, and Cinitapride for a month. After a month, I was still the same.
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. 1 step has no time and sits in story order between the steps around it. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| 2024 | constant severe nausea began, followed by fatigue and burning in limbs and neckA year ago, I began experiencing extreme and chronic nausea that has lasted to this day.In context ↗ | Moderate |
| — | symptoms worsened after 14-day H. pylori quadruple therapyHowever, there was no improvement in my symptoms, and they even worsened.In context ↗ | Moderate |
| 2025-06-27 | still nauseated, weak and breathless, with no diagnosisI've been suffering from various gastrointestinal and neurological symptoms for the past year, for which the doctors can't find an explanation or a cause.In context ↗ | Moderate |
Adverse events
- Antibiotics (unspecified)“He prescribed quadruple therapy for 14 days, which I completed. However, there was no improvement in my symptoms, and they even worsened.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Gut problems
extreme and chronic nausea that has lasted to this day
In context ↗ - Muscle weakness
extreme and chronic fatigue in my limbs and neck
In context ↗ - Breathlessness
I've also recently started experiencing a intense and permanent shortness of breath
In context ↗ - Anxiety & low mood
I've been quite depressed lately
In context ↗