ME/CFS
Outcome unclear
Joint resorption and MCAS with ME/CFS; PRF injections and low-dose naltrexone tried
- Condition
- ME/CFS
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Feb 2026
In their words
- Condition: ME/CFS
Yes! Like you, I had histamine reactions to LDN; you're not alone in this.
In context ↗
Summary
A person with joint resorption and MCAS reported that PRF injections stopped their joints resorbing and eased pain; CT scans six months apart showed stable joints and damaged discs beginning to heal. Low-dose naltrexone raised their urticaria in a dose-dependent way, so after three weeks without improvement they stopped it, hoping to try it again while treating their MCAS.
Ask Miruvor AI
What they tried
Also tried
Their words about each treatment
- PRF injections · Helped a lot
PRF injections stopped my joints resorption. Very effective for pain as well
In context ↗ - shakes (bananas + oats + peanut butter/coconut milk) · Helped
I gained weight by blending together bananas + oats + peanut butter/coconut milk
In context ↗ - LDN · Worse
My urticaria shot through the roof. It was dose-dependent in my case.
In context ↗
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened |
|---|---|
| — | became ill with joint degeneration and MCASPRF injections stopped my joints resorption.In context ↗ |
| 2023-10-30 | PRF injections stopped joint resorption and eased painPRF injections stopped my joints resorption. Very effective for pain as wellIn context ↗ |
| 2026-02-01 | still treating MCAS; LDN stopped after three weeks without improvementI'm in the process of treating my MCAS, and I hope to reintroduce it soon.In context ↗ |
Adverse events
- Low-dose naltrexone“I had histamine reactions to LDN; you're not alone in this. ... My urticaria shot through the roof. It was dose-dependent in my case.” In context ↗ Allergic reaction / anaphylaxis
Symptoms mentioned
Their words about their symptoms
- Mast cell (MCAS) & allergies
I'm in the process of treating my MCAS, and I hope to reintroduce it soon.
In context ↗ - Pain & fibromyalgia
Very effective for pain as well
In context ↗