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ME/CFS Moderate → much better

ME/CFS with fatigue and fibromyalgia, much better on modafinil and Adderall

Condition
ME/CFS
At worst
Moderate (mostly housebound)
Ill before improving or writing
Not stated
Last post
Jul 2025
In their words
  • Condition: ME/CFSMy doctor prescribed modafinil for wakefulness/chronic fatigue In context ↗
  • At worst: ModerateI’m certainly not as functional as a healthy person, but Im not sleeping during the day, I don’t need naps In context ↗
  • Now: Much betterI’m certainly not as functional as a healthy person ... it’s been almost a year and I’m doing really well.
Read from 3 of their posts and comments; links to the 3 this page draws on

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Summary

A Reddit user with chronic fatigue and fibromyalgia reported that modafinil for wakefulness and chronic fatigue helped: they were not sleeping during the day, did not need naps, and barely needed rest other than breaks between tasks and downtime. Almost a year on modafinil plus Adderall they were doing really well. They remained less functional than a healthy person, and had not found a way to resolve shoulder blade pain other than a shoulder/back brace and steroids.

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What they tried

Also tried

shoulder and back brace· Not saidsteroids· Not said
Their words about each treatment
  • modafinil · HelpedMy doctor prescribed modafinil for wakefulness/chronic fatigue and it definitely helps me. In context ↗
  • adderall · HelpedI also have adhd and take adderall along with it, it’s been almost a year and I’m doing really well. In context ↗
  • shoulder and back brace · Not saidI haven’t found a way to resolve it yet other than wearing a shoulder and back brace and steroids. In context ↗

Approaches: Stimulants

Their path

What they say at each step doesn’t fit the worst point or outcome above on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happenedAfter
—ME/CFS with daytime sleepiness and daily naps, before any medicationMy doctor prescribed modafinil for wakefulness/chronic fatigue In context ↗
2025-05-05modafinil stopped daytime sleeping and naps; still less functional than a healthy personMy doctor prescribed modafinil for wakefulness/chronic fatigue and it definitely helps me. In context ↗Modafinil / armodafinil
2025-05-05almost a year on modafinil plus Adderall, doing really wellI also have adhd and take adderall along with it, it’s been almost a year and I’m doing really well. In context ↗Amphetamine salts (Adderall)

Symptoms mentioned

Their words about their symptoms
  • Pain & fibromyalgiaI also have fibro and suspected connective tissue disorder. In context ↗
  • Sleep problemsIm not sleeping during the day, I don’t need naps In context ↗

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