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Condition not stated Moderate → somewhat betterIll 3 years before improving or writing

Years of brain fog and fatigue upright, some improvement after medication changes

Condition
Condition not stated
At worst
Moderate (mostly housebound)
Ill before improving or writing
3 years
Last post
Jul 2025
In their words
  • Condition: Condition not statedSo maybe this isn’t “true” ME/CFS but some kind of **central dysregulation** In context ↗
  • At worst: ModerateI feel better in the morning, then gradually deteriorate the longer I stay upright or stimulated. In context ↗
  • Now: Somewhat betterI’m not as unwell as I was three years ago, but I have improved overall since then. In context ↗
  • Says they never had: Headaches & migraineI don’t get headaches, pain, or heart rate spikes.
  • Says they never had: Heart symptoms & palpitationsI don’t get headaches, pain, or heart rate spikes.
  • Says they never had: POTS & dysautonomiaI’m *not* diagnosed with POTS — I have no tachycardia, no fainting, no dizziness.
  • Says they never had: Pain & fibromyalgiaI don’t get headaches, pain, or heart rate spikes.
Read from 4 of their posts and comments; links to the 3 this page draws on

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Summary

A Reddit user described a disabling condition lasting over three years that began after they stopped long-term Lexapro: brain fog and mental fatigue building while upright, sensory intolerance, and relief only when lying flat. Antidepressants, anxiolytics and mood stabilisers brought no lasting relief. Altered psychiatric medications this year gave slight gains; they said they were less unwell than three years earlier but still not as well as they should be.

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What they tried

Their words about each treatment
  • Lexapro (SSRI) · Not saidthis entire issue began shortly after quit Lexapro (SSRI) In context ↗
  • antidepressants · No changeI’ve tried antidepressants, anxiolytics, and mood stabilizers — no lasting relief In context ↗
  • sleep aids · Not saidincluding sleep aids, SSRIs, anxiolytics, and antipsychotics In context ↗
  • rest / lying down · Helpedwhen I lie down, symptoms reduce, sometimes significantly In context ↗
  • deep breathing · HelpedRelief only comes from lying fully flat, especially with deep breathing In context ↗

Their path

Very severeSevereModerateMildNear normalRecoveredonset12 mo2 y3 y

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.

Show as a table
WhenWhat happenedWhere they were
~2022 (three years before July 2025)illness began after stopping long-term Lexapro; worst point, not as unwell sincefor me this entire issue began shortly after quit Lexapro (SSRI) In context ↗Moderate
2025-07-06improved overall but still crashes daily when upright; psychiatric medications altered this year with slight gainsI’m not as unwell as I was three years ago, but I have improved overall since then. In context ↗Moderate

Symptoms mentioned

Their words about their symptoms
  • Brain fogHeavy “brain fog” that worsens with time upright — feels like internal shutdown or derealization In context ↗
  • Post-exertional malaiseI actually *do* experience worsening after mental or physical exertion — but in my case it happens within the same day In context ↗
  • Light & noise sensitivitySensory intolerance — noise, lights, conversation feel unbearable In context ↗
  • Anxiety & low moodOccasional emotional overstimulation when fatigued (like panic or inner pressure) In context ↗

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