Long COVID
Outcome unclear
Long COVID with POTS and mast cell problems, tried acyclovir
- Condition
- Long COVID
- At worst
- Not stated
- Ill for
- Not stated
- Last post
- Sep 2026
In their words
- Condition: Long COVID
r/covidlonghaulers
In context ↗
Read from 5 of their posts and comments; links to the 5 this page draws on
Summary
A person with long COVID, POTS and mast cell problems said they felt better while taking acyclovir, and that their thyroid was also better on it. They linked digestion problems from their GLP-1 to reactivated POTS and a mast cell flare. Taking something for weeks helped their gut, but they could not sleep.
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What they tried
Also tried
Their words about each treatment
- acyclovir · Helped
I feel better when I take acyclovir. My thyroid is also better while I’m on it
In context ↗ - glp1 · Worse
I think digestion issues from my glp1 has reactivated pots and caused mast cell flare
In context ↗ - custom probiotics d lactate free · Helped
Can a reaction to these be insomnia? I know they are helping my gut
In context ↗ - Probiotics and fermented foods · Not said
Can a reaction to these be insomnia? I know they are helping my gut ... I've been taking them for weeks but I can't sleep. Might not be rebated
Their path
They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| — | ill with long COVID, POTS and mast cell problems; onset not describedI also feel better when on acyclovirIn context ↗ | |
| 2026-07-22 | felt better on acyclovir, thyroid better tooI feel better when I take acyclovir. My thyroid is also better while I’m on itIn context ↗ | Acyclovir |
| 2026-07-22 | digestion problems from GLP-1 reactivated POTS and set off a mast cell flareI think digestion issues from my glp1 has reactivated pots and caused mast cell flareIn context ↗ | |
| 2026-09-10 | custom D-lactate-free probiotic helping gut, but weeks of insomniaI know they are helping my gutIn context ↗ |
Adverse events
- GLP-1 drugs (unspecified)“I think digestion issues from my glp1 has reactivated pots and caused mast cell flare” In context ↗ Gut side effects
- GLP-1 drugs (unspecified)“I think digestion issues from my glp1 has reactivated pots and caused mast cell flare” In context ↗ Autoimmune or inflammatory flare
- Probiotics and fermented foods“Can a reaction to these be insomnia? I know they are helping my gut ... I've been taking them for weeks but I can't sleep. Might not be rebated” Insomnia from treatment
Symptoms mentioned
Their words about their symptoms
- Gut problems
digestion issues from my glp1
In context ↗ - POTS & dysautonomia
has reactivated pots
In context ↗ - Mast cell (MCAS) & allergies
caused mast cell flare
In context ↗