ME/CFS too exhausted to travel home, now much better with peptides and melatonin
- Condition
- ME/CFS
- At worst
- Mild (working or studying, with limits)
- Ill before improving or writing
- 14 years
- Last post
- May 2024
In their words
- Condition: ME/CFS
COVID was one part of my medical situation (CFS since 2010, Type II Narcolepsy, and then COVID made everything worse)
In context ↗ - At worst: Mild
Fridays are usually bad days due to accumulated week at work (I work a full time job in terms of workload in part time hrs)
In context ↗ - Now: Much better
I have taken it for 1 week total and I feel “GREAT” for first time in ~15 years
In context ↗
Read from 7 of their posts and comments; links to the 5 this page draws on
Summary
Harbor 54386 had ME/CFS from 2010 plus type II narcolepsy, worsened by COVID, and as of spring 2024 was working a full-time workload in part-time hours, resting for hours on bad days and too exhausted at Christmas 2023 to travel home. A functional doctor gave a 40-60% improvement. In spring 2024 SS-31 and other peptides plus 180 mg melatonin left them feeling great for the first time in 15 years, cycling 10 miles.
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What they tried
What they credit
Also tried
Their words about each treatment
- functional doctor · Helped a lot
Then I found a functional doctor that helped figure out what 4 sleep docs missed at top hospitals. I got 40 - 60% better.
In context ↗ - BPC-157 · Worse
BPC-157 (oral capsule). Took 1 cap and had a lot of problems
In context ↗ - Cerebrolysin · Helped
I took 1 ml for 9 days ... several days were great before effects wore off
In context ↗ - high dose melatonin · Helped
my sleep is getting better with the high dose melatonin. I'm waking up earlier.
In context ↗ - Thymosin-Alpha 1 · Not said
Thymosin-Alpha 1 ... no issues to date with recommended dose from A4M
In context ↗ - Thymosin-Beta 4 Fragment · Not said
Thymosin-Beta 4 Fragment (oral) note this is not full molecule - I had no issues to date with recommended dose on bottle which agrees with A4M
In context ↗ - SS-31 · Helped a lot
the addition of SS-31 in particular is responsible for major energy improvements
In context ↗ - TMG supplement · Not said
TMG Supplement (need to use with SS-31) ... I purchased and take Allergy Research
In context ↗ - Trazodone · Worse
taking with Trazodone caused problems for me
In context ↗ - Xywav · Not said
inability to get deep sleep or fall asleep without a medication called Xywav
In context ↗
Approaches: Alternative therapies · Peptides · Supplements
Their path
What they say at each step doesn’t fit the worst point or outcome above on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened |
|---|---|
| 2010 | ME/CFS and type II narcolepsy beganCFS since 2010, Type II Narcolepsy, and then COVID made everything worseIn context ↗ |
| — | kept worsening through years and 38 doctors, later worsened by COVIDthings kept getting worse and worse. I saw over 38 doctors at the time and many were nice but didn’t help.In context ↗ |
| — | first functional doctor found what sleep doctors missed; 40-60% betterI got 40 - 60% better. It was huge. But still very tough.In context ↗ |
| December 2023 | too exhausted to travel home for Christmasin December 2023 over Christmas Holiday I was so exhausted I didn't go home to see my familyIn context ↗ |
| April 2024 | peptides and high-dose melatonin brought major energy gainsAnd the addition of SS-31 in particular is responsible for major energy improvements.In context ↗ |
| 2024-05-20 | reporting significant recent improvementsI was very athletic before my situation and recently have had significant improvements!In context ↗ |
Adverse events
- BPC-157“I was super sensitive it affected my blood pressure (went low)” In context ↗ Low blood pressure or fainting
- BPC-157“I did not feel right also was sweating hot then cold for hours” In context ↗ Side effects
- Cerebrolysin“I took 1 ml for 9 days - and that was PLENTY. I felt a bit over stimulated for a few days after last dose” In context ↗ Side effects
- Cerebrolysin“taking with Trazodone caused problems for me” In context ↗ Other
Symptoms mentioned
Their words about their symptoms
- Sleep problems
This has been a major problem with my Narcolepsy (for me it presents in the inability to get deep sleep or fall asleep without a medication called Xywav).
In context ↗ - Post-exertional malaise
when its bad I have to lay down and just rest and not move for hours until energy comes back
In context ↗
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