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Peptides

343 people credit peptides as one reason they got better overall (96 with ME/CFS, 245 with long COVID, 2 (few people) not stated).

Everyone · 943 people

All 943 who tried one of its treatments

How it went for everyone who tried one of its treatments

Helped means they said it helped with what they took it for, which may be one symptom and not the illness. Each person counts once: someone who tried several of these treatments is split equally across those they said how it went for.

69%
helped
576 of 831
15%
no change
122 of 831
16%
got worse
133 of 831

Shares are out of the 831 people who said how it went for at least one of them, each counted once, the parts rounded to whole people. 112 more tried one or credit the approach without saying how it went.

Show as a table
How it wentPeopleShare
Helped a lot18122%
Helped39547%
No change12215%
Worse11514%
Much worse182%

Everyone · 343 people

343 who credit it

Among the 343 who credit it with their improvement, here’s how they are now

Credit it means they say it’s one reason they got better.

26%
recovered or near normal
90 of 343
64%
much or somewhat better
218 of 343
10%
relapsed
35 of 343

Where each person was at the end of their story, or in their latest post that says how they are, compared with their worst point.

Show as a table
Outcome describedPeopleShare
Recovered247%
Near normal6619%
Much better10130%
Somewhat better11734%
Relapsed3510%

Did it last?

  • 34 of 343 said the benefit of a treatment in this approach wore off (11 of them among the 35 who relapsed).
  • 164 of 343 say they still need to keep doing something (not always one in this approach) to stay well.

Read from what people wrote, and the more someone wrote, the more likely they are to mention it. Some people stop posting before saying, so the real number may be higher.

343 who credit it

By how ill people were

Only the 343 who credit this approach, so people it didn’t help or made worse aren’t here. How they are now is their outcome overall.

Severity at worstHow they are nownRecovered or near normal
Mild6430%
Moderate6237%
Severe11326%
Very severe157%
Not stated8920%
Show as a table
At worstOutcomePeopleShare
MildRecovered4 of 646%
MildNear normal15 of 6424%
MildMuch better17 of 6427%
MildSomewhat better20 of 6431%
MildRelapsed8 of 6412%
ModerateRecovered3 of 625%
ModerateNear normal20 of 6232%
ModerateMuch better15 of 6224%
ModerateSomewhat better19 of 6231%
ModerateRelapsed5 of 628%
SevereRecovered9 of 1138%
SevereNear normal20 of 11318%
SevereMuch better47 of 11342%
SevereSomewhat better25 of 11322%
SevereRelapsed12 of 11310%
Very severeRecovered1 of 157%
Very severeMuch better8 of 1553%
Very severeSomewhat better4 of 1527%
Very severeRelapsed2 of 1513%
Not statedRecovered7 of 898%
Not statedNear normal11 of 8912%
Not statedMuch better14 of 8916%
Not statedSomewhat better49 of 8955%
Not statedRelapsed8 of 899%

Treatments in this approach

Bar: how it went for everyone on the site who tried it and said so. Recovered and Faded: of the people here who credit it.

The bar (How it went) and the line under each name are among everyone on the site who tried it and said how it went, the same numbers as on each treatment’s own page. Recovered and Faded are among the people here who credit it. Grey numbers rest on fewer than 10 people; a faded share in red is a third or more.

Fewer than 3 people here credit these, so they aren’t ranked: DSIP.

Everyone · 343 people

20 of the 343 people

See all 343 stories
  • Long COVID crashes and wrecked gut, now near normal on antihistamines and diet

    Near normal Badger 97535 Long COVID Mild at worstIll 5.5 years before improving or writing reddit.com Oct 2026

    Badger 97535 developed long COVID after a covid infection in early 2021. He worked through months of 2-4 hours' sleep early on, a wrecked gut, mast cell reactions and flu-like crashes after exercise. Antihistamines, keto and very-low-calorie diets, PEA,…

  • Long COVID too faint to walk or drive, now good most days at about 80-85%

    Much better Grove 43730 Long COVID Moderate at worstIll 6 months before improving or writing reddit.com Oct 2026

    A woman who fell ill with long COVID in August 2023 was too faint to walk around much or drive, with brain fog, breathlessness and anxiety. Quitting her job and resting six months, plus supplements, brought her to about 90% by mid-2024, but a January 2025…

  • Often bedbound with long COVID, now almost back to normal after diet and rowing regimen

    Near normal Osprey 74759 Long COVID Ill 2.5 years before improving or writing reddit.com Oct 2026

    Osprey 74759 fell ill with long COVID in October 2020 and after about 2.5 years was often bedbound, unable to walk 100 m without near-fainting. In 2023 a self-designed supplement, diet and rowing-machine regimen produced rapid gains: from bedridden to…

  • Long COVID made work impossible, now somewhat better with pacing and GLP-1 drugs

    Somewhat better Puffin 16593 Long COVID Severe at worstIll 4.5 years before improving or writing reddit.com Oct 2026

    He caught COVID in 2022 during Omicron when his son started daycare and kept getting sicker as daycare infections piled up; symptoms peaked about a year in and work became impossible. He improved after a long COVID clinic helped with management and he…

  • Long COVID with PEM and brain fog, now close to normal after keto and fasting

    Near normal Lake 45346 Long COVID Severe at worstIll 4 years before improving or writing reddit.com Oct 2026

    Lake 45346 got long COVID after a COVID infection in August 2022 and had PEM, brain fog, broken sleep and carb intolerance. He credits keto, fasting, fermented foods, low-dose naltrexone, cold plunges, nightly guanfacine, sauna and high-dose thiamine TTFD…

  • Mostly housebound with long COVID, head pressure and POTS, somewhat better with SS31

    Somewhat better Prairie 45553 Long COVID Moderate at worstIll 2 years before improving or writing reddit.com Oct 2026

    A student-athlete in Switzerland fell ill in September 2024 during boxing camp and was mostly housebound 18 months later, with head pressure, neck stiffness, tinnitus, POTS and crashes after exertion or social contact. Melatonin seemed to fix his sleep and…

  • Long COVID, anhedonia and blank mind; rifaximin helped, then a fifth course worsened it

    Relapsed Birch 37328 Long COVID Severe at worstIll 4 years before improving or writing reddit.com Oct 2026

    Long COVID followed a COVID infection in July 2022, with anhedonia, blank mind, emotional blunting and genital numbness, plus possible MCAS, POTS and SIBO. Rifaximin in 2023 helped, while methylene blue, NAD, plasmapheresis, SCIG and steroids gave only…

  • Badly affected by long COVID for months, now nearly back to normal with time and LDN

    Near normal Wave 20769 Long COVID Moderate at worstIll 4 months before improving or writing reddit.com Oct 2026

    They fell ill with COVID in December 2024 and were badly affected for months, taking three months off work on medical leave with brain fog, DPDR, lost smell and numbness. Gradual improvement came with time, PEA with luteolin, LDN, HIIT with oxygen and…

  • Long COVID with PEM and brain fog, now much better with low-dose naltrexone and KPV

    Much better Mesa 33420 Long COVID Mild at worstIll 6 years before improving or writing reddit.com Oct 2026

    Mesa 33420 has had long COVID since 2020, with PEM, brain fog, MCAS, gut problems and low mood, while working full time in the military. Tollovid and hydroxychloroquine gave only temporary relief, and tollovid was followed by a hard relapse; it cost $1,200.…

  • Bedbound with long COVID, now much better after pacing and ozone therapy

    Much better Nightjar 39576 Long COVID Very severe at worstIll 4 years before improving or writing reddit.com Oct 2026

    They fell ill with long COVID in September 2022 after a second infection, bedbound and very severe at first. Improvement was very slow: they credited ozone therapy, weekly 72-hour fasts, NAD+ IVs (€207 each) and later home injections, the KPV peptide and…

  • Bedridden with ME/CFS, now much better with aggressive rest and immune globulin

    Much better Stream 28708 ME/CFS Severe at worstIll 10 years before improving or writing reddit.com Oct 2026

    Developed ME/CFS at 13 after mononucleosis and became bedridden with months of rolling PEM, worsened by exercise addiction and a COVID vaccine. Aggressive rest plus subcutaneous immune globulin (20 g/week), testosterone, growth hormone and peptides took him…

  • Long COVID exhaustion, improved then relapsed; magnesium chloride helped POTS

    Relapsed Hill 43253 Long COVID Mild at worst reddit.com Oct 2026

    Hill 43253 had long-standing exhaustion and in January 2022 caught Omicron, which laid them low for about a week before they returned to 70-80% of pre-COVID energy. By late 2023 they were at roughly 50% of normal and could train cautiously in the gym without…

  • Bedbound with severe ME/CFS, now back to mild after stellate ganglion blocks and rest

    Much better Beech 14261 ME/CFS Severe at worstIll 5 years before improving or writing reddit.com Oct 2026

    Beech 14261 fell ill after a viral infection and became bedbound with severe ME/CFS, unable to digest food for a year and losing muscle fast. Over about two years of stellate ganglion blocks, peptides, supplements, LDN, protein and rest they worked back to…

  • Long COVID with fatigue, PEM and POTS, now nearly back to normal after nicotine patches

    Near normal Valley 17483 Long COVID Mild at worstIll 6.5 years before improving or writing reddit.com Oct 2026

    Since April 2020 they had long COVID, mostly at 70–90% of normal with fatigue, PEM and POTS, then neck pain and brain fog after a December 2023 reinfection. Two Pfizer shots gave an eight-month remission in 2021; BPC-157/TB-500, nicotine patches, tirzepatide…

  • Bedbound for months with long COVID, now much better after Augmented NAC

    Much better Maple 34332 Long COVID Severe at worstIll 4 years before improving or writing reddit.com Oct 2026

    Three COVID infections left them disabled with EBV reactivation, B12 deficiency and gut dysbiosis, and they were bedbound for months in 2023. High-dose B12 and a Biomesight gut protocol got them back to work at about 85%, until a GI virus and a lupus SLE…

  • Bedridden with long COVID, now much better after nicotine patches and LDN

    Much better Sparrow 25292 Long COVID Severe at worstIll 2 months before improving or writing reddit.com Oct 2026

    Sparrow 25292, a person in India, developed long COVID in late 2023 with fatigue and PEM; a stomach infection and antibiotics in January 2024 left them bedridden and unable to hold a bottle. Nicotine patches, nattokinase, LDN, COQ10, methylene blue, DCA and…

  • Long COVID with daily migraines, PEM and POTS, now almost back to normal after pacing

    Near normal Glade 22757 Long COVID Moderate at worstIll 6 years before improving or writing reddit.com Oct 2026

    Glade 22757 has had long COVID since 2020, with daily migraines, PEM, MCAS, POTS and light, sound and smell sensitivity. Pushing through the first two to three years made them worse, so they quit work and slowed down. Pacing, scheduled rest, vestibular…

  • Long COVID with brain fog and dysautonomia, now nearly back to normal after peptides

    Near normal Sandpiper 68276 Long COVID Mild at worst reddit.com Oct 2026

    A Reddit user with long COVID, MCAS, dysautonomia, mould and Lyme. Peptides (SS-31, MOTS-C, Cortexin, Cortagen) gave the biggest gains, clearing most brain fog and raising energy; mould treatment eased dysautonomia and oral cromolyn helped digestion. By…

  • ME/CFS with exercise intolerance, fibromyalgia and PEM, somewhat better on MOTS-c and NAD+

    Somewhat better Zephyr 27058 ME/CFS Mild at worstIll 4 years before improving or writing reddit.com Oct 2026

    Zephyr 27058 has ME/CFS with exercise intolerance, fibromyalgia and PEM that wrecked the rest of the day after each jiu-jitsu class. Testosterone for clinically low levels ended their panic attacks, and MOTS-c and NAD+ taken before exercise eliminated…

  • Largely bedbound with long COVID, now somewhat better, crediting niacin and melatonin

    Somewhat better Trail 96635 Long COVID Severe at worstIll 6 years before improving or writing reddit.com Oct 2026

    A person in Illinois fell ill in March 2020 (COVID not confirmed) and by around 18 months was largely bedbound, with breathlessness, panic attacks and brain fog. They improved slowly from around month 17, crediting niacin, melatonin, thiamine and vitamin D.…

The newest 20 people who credit peptides.

A little hope, every Sunday

New recovery stories and data-driven research on ME/CFS and long COVID. Ideas worth considering, and the evidence behind them.

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