ME/CFS with complete fatigue, now nearly back to normal on clarithromycin and benfotiamine
- Condition
- ME/CFS
- At worst
- Severe (mostly bedbound)
- Ill before improving or writing
- Not stated
- Last post
- Aug 2025
In their words
- Condition: ME/CFS
I had sinusitis and along with that complete fatigue.
In context ↗ - At worst: Severe
I would be bedridden without it and I now have a normal life.
In context ↗ - Now: Near normal
It has given me my life back. ... I would be bedridden without it and I now have a normal life.
In context ↗ - Began after: a bacterial or tick-borne infection
I had sinusitis and along with that complete fatigue.
In context ↗
Summary
They described sinusitis with complete fatigue and said they would be bedridden without clarithromycin. They took clarithromycin 500 mg twice daily, four days on and three off, for 20 years, which they said gave them their life back. Benfotiamine also helped their fatigue; after five years off clarithromycin they felt very fatigued, and by August 2025 they reported a normal life.
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What they tried
What they credit
Also tried
Their words about each treatment
- Clarithromycin · Helped a lot
It has given me my life back.
In context ↗ - acidophilus · Helped
It is very important to take acidophilus one hour after clarithromycin morning and night.
In context ↗ - BENFOTIAMINE · Helped
that also helps my fatigue
In context ↗
Approaches: Antibiotics
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| onset | sinusitis with complete fatigue; bedridden without clarithromycinI had sinusitis and along with that complete fatigue. ... I would be bedridden without itIn context ↗ | Severe | |
| 20 years of treatment before 2025 | started pulse-dose clarithromycin; life backIt has given me my life backIn context ↗ | Near normal | Clarithromycin (Biaxin) |
| April 2025 (off it for five years) | stopped clarithromycin; very fatiguedI have been off it for 5 years. I am noticing that off it I am very fatigued.In context ↗ | Not stated | |
| August 2025 | back on clarithromycin pulse therapy plus benfotiamine; normal lifeI would be bedridden without it and I now have a normal lifeIn context ↗ | Near normal | Clarithromycin (Biaxin) |
Adverse events
- Clarithromycin (Biaxin)“Yes, it does give a weird taste in your mouth but I would rather have that than the tiredness, you can chew gum.” In context ↗ Side effects
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