Bedridden with long COVID over two years, now close to normal after Paxlovid and Thymosin
- Condition
- Long COVID
- At worst
- Severe (mostly bedbound)
- Ill before improving or writing
- 2.5 years
- Last post
- Oct 2025
In their words
- Condition: Long COVID
I started both almost at the same time since I was throwing the kitchen sink at the LC
In context ↗ - At worst: Severe
I’ll take it over the alternative bed ridden life I’ve become accustomed to
In context ↗ - Now: Near normal
I have 59 gym visits logged and I am training for my first 5K. My VO2 Max score is still below normal
In context ↗ - Began after: COVID
2+ yrs of LC will do that to you
In context ↗
Read from 8 of their posts and comments; links to the 5 this page draws on
Summary
They were bedridden with long COVID for over two years, using TRT and creatine to stay afloat. After a second COVID infection they took Paxlovid and Thymosin Alpha-1 and got back to about 85-90% of their old self and into the gym, though they weren't sure which helped. A large serving of pineapple set off a histamine flare that a second course of Thymosin reversed. They now train for their first 5K, with VO2 max still below normal.
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What they tried
Also tried
Their words about each treatment
- TRT · Helped
I stayed on my TRT protocol which kept me above water for about two years.
In context ↗ - creatine · Helped
TRT and creatine helped keep me afloat, but nothing like TA-1.
In context ↗ - a ton of water · Helped
For me it was creatine 5 g daily, TRT, and a ton of water.
In context ↗ - BPC-157 · No change
That did nothing for me either.
In context ↗ - Plaxovid · Not said
I’m not sure if it was the dose of Plaxovid I took since I caught COVID for a second time or the Thymosin Alpha 1.
In context ↗ - Thymosin Alpha 1 · Helped a lot
I ran one vial over a few weeks and for the first time in two years most of my issues finally cleared up.
In context ↗
Approaches: Peptides · Sex hormones · Supplements
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. The first step with a time is 2 years after onset: the story doesn’t say how ill they were before that. The dashed part: the story doesn’t say when. 2 steps say too little to place on the scale and are only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| 2022 | long COVID2+ yrs of LC will do that to youIn context ↗ | Not stated | |
| — | bedridden with long COVIDthe alternative bed ridden life I’ve become accustomed toIn context ↗ | Severe | |
| December 2024 | back to about 85% of their old self, started gymnow I’m back to my old self (~85% back)In context ↗ | Mild | Thymosin alpha-1 (Ta1) |
| June 2025 | histamine flare after eating fresh pineappleIt set off what felt like a histamine storm and I felt wrecked all over againIn context ↗ | Not stated | |
| October 2025 | back in the gym, training for first 5KI have 59 gym visits logged and I am training for my first 5KIn context ↗ | Near normal | Thymosin alpha-1 (Ta1) |
Symptoms mentioned
Their words about their symptoms
- Mast cell (MCAS) & allergies
staying away from fresh pineapple since it caused me to flare up for days
In context ↗
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