ME/CFS with 15-60 minutes of clarity a day, now somewhat better with NMN and multivitamins
- Condition
- ME/CFS
- At worst
- Severe (mostly bedbound)
- Ill before improving or writing
- Not stated
- Last post
- Aug 2026
In their words
- Condition: ME/CFS
before I realized I have me/cfs
In context ↗ - At worst: Severe
usually I only have 15-60’ of clarity a day
In context ↗ - Now: Somewhat better
A combo NMN + Ashwagandha + B12 in the morning on selective days really helps energy boost and prolonged clarity
In context ↗
Read from 5 of their posts and comments; links to the 4 this page draws on
Summary
They had ME/CFS for at least two years, unrecognised at first. Wellbutrin XL helped a little before side effects built up, and ADHD stimulants left them trembling and needing child-sized chopsticks. NMN with ashwagandha and B12 lengthened their daily mental clarity from 15-60 minutes to two to six hours, and multivitamins helped fill nutrient gaps from a restricted diet. They remained ill, with tremors and itchiness persisting after stopping all medication.
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What they tried
What they credit
Also tried
Their words about each treatment
- Wellbutrin XL (NDRIs) · Helped
I took Wellbutrin XL (NDRIs) around 2 years back when I have cfs but didn’t know, it really helps, not a lot but better than nothing
In context ↗ - ADHD stimulants · Worse
then I got prescribed ADHD stimulants for well duh ADHD, and god my body was trembling, stairs, platforms, and any hand movements that need details became a nightmare
In context ↗ - meds for anxiety · Not said
I was on antidepressants and meds for adhd and anxiety, before I realized I have me/cfs.
In context ↗ - multivitamins · Helped
multivitamins or specifics combo of vitamins really helps in the long run
In context ↗ - NMN · Helped
A combo NMN + Ashwagandha + B12 in the morning on selective days really helps energy boost and prolonged clarity
In context ↗ - lightly boiled vegetables / vegetable soup diet · Not said
THE ONLY safe diet that I can consume mainly consists of lightly boiled vegetables or some sort of vegetables soup (leafy greens)
In context ↗
Approaches: Other antidepressants · Supplements
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| onset | ME/CFS began, not recognised at the timeI took Wellbutrin XL (NDRIs) around 2 years back when I have cfs but didn’t knowIn context ↗ | Not stated | |
| around 2 years before December 2025 | rock bottom before starting Wellbutrinwhen you’re at rock bottom (or desperate enough), Wellbutrin (or everything and anything) is worth a tryIn context ↗ | Severe | |
| around 2 years before December 2025 | Wellbutrin XL helped a little, side effects built up laterit really helps, not a lot but better than nothingIn context ↗ | Severe | Bupropion (Wellbutrin) |
| — | ADHD stimulants caused trembling and loss of fine hand controlgod my body was trembling, stairs, platforms, and any hand movements that need details became a nightmareIn context ↗ | Severe | |
| March 2026 | NMN with ashwagandha and B12 lengthened clarity to 2-6 hours a dayusually I only have 15-60’ of clarity a day, now 2-6 hours depending on the dayIn context ↗ | Moderate | NAD+ boosters (NMN, nicotinamide riboside, NADH, ATP) |
| 2026-08-11 | still ill; medication side effects persist after stopping all medsEven when I stopped all meds, side effects persists, while reduced compare to when I was prescribedIn context ↗ | Moderate |
Adverse events
- Bupropion (Wellbutrin)“over time it builds up the side effects ... For the first year of Wellbutrin, I felt absolutely no side effects, but it started appearing after I get better.” Side effects
- Stimulants (unspecified)“god my body was trembling, stairs, platforms, and any hand movements that need details became a nightmare, I had to even buy kid chopsticks to able to use a chopstick” In context ↗ Side effects
- Bupropion (Wellbutrin)“Even when I stopped all meds, side effects persists, while reduced compare to when I was prescribed, it left lasting impacts, physical tremors” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Brain fog
usually I only have 15-60’ of clarity a day, now 2-6 hours depending on the day
In context ↗ - Sleep problems
I had tinnitus and really terrible insomnia way before Wellbutrin
In context ↗ - Anxiety & low mood
I have severe anxiety, chronic depression, GERD, autism, and of course CFS + ADHD
In context ↗ - Gut problems
I have severe anxiety, chronic depression, GERD
In context ↗ - Temperature regulation
blood flows irregularly creating itchiness similar to allergic reactions due to temperature based sensitivity
In context ↗
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