How it went for everyone who tried one of its treatments
Helped means they said it helped with what they took it for, which may be one symptom and not the illness. Each person counts once: someone who tried several of these treatments is split equally across those they said how it went for.
Shares are out of the 4,091 people who said how it went for at least one of them, each counted once, the parts rounded to whole people. 658 more tried one or credit the approach without saying how it went.
| How it went | People | Share |
|---|---|---|
| Helped a lot | 530 | 13% |
| Helped | 2,393 | 59% |
| No change | 334 | 8% |
| Worse | 785 | 19% |
| Much worse | 49 | 1% |
Among the 1,087 who credit it with their improvement, here’s how they are now
Credit it means they say it’s one reason they got better.
Where each person was at the end of their story, or in their latest post that says how they are, compared with their worst point.
| Outcome described | People | Share |
|---|---|---|
| Recovered | 36 | 3% |
| Near normal | 146 | 14% |
| Much better | 362 | 33% |
| Somewhat better | 412 | 38% |
| Relapsed | 130 | 12% |
| Outcome unclear | 1 | — |
Did it last?
- 48 of 1,087 said the benefit of a treatment in this approach wore off (21 of them among the 130 who relapsed).
- 615 of 1,087 say they still need to keep doing something (not always one in this approach) to stay well.
How it went for everyone who tried one of its treatments
Helped means they said it helped with what they took it for, which may be one symptom and not the illness. Each person counts once: someone who tried several of these treatments is split equally across those they said how it went for.
Shares are out of the 2,688 people who said how it went for at least one of them, each counted once, the parts rounded to whole people. 421 more tried one or credit the approach without saying how it went.
| How it went | People | Share |
|---|---|---|
| Helped a lot | 379 | 14% |
| Helped | 1,565 | 58% |
| No change | 213 | 8% |
| Worse | 503 | 19% |
| Much worse | 28 | 1% |
Among the 756 who credit it with their improvement, here’s how they are now
Credit it means they say it’s one reason they got better.
Where each person was at the end of their story, or in their latest post that says how they are, compared with their worst point.
| Outcome described | People | Share |
|---|---|---|
| Recovered | 31 | 4% |
| Near normal | 134 | 18% |
| Much better | 255 | 34% |
| Somewhat better | 251 | 33% |
| Relapsed | 85 | 11% |
Did it last?
- 32 of 756 said the benefit of a treatment in this approach wore off (14 of them among the 85 who relapsed).
- 416 of 756 say they still need to keep doing something (not always one in this approach) to stay well.
How it went for everyone who tried one of its treatments
Helped means they said it helped with what they took it for, which may be one symptom and not the illness. Each person counts once: someone who tried several of these treatments is split equally across those they said how it went for.
Shares are out of the 1,388 people who said how it went for at least one of them, each counted once, the parts rounded to whole people. 227 more tried one or credit the approach without saying how it went.
| How it went | People | Share |
|---|---|---|
| Helped a lot | 149 | 11% |
| Helped | 820 | 59% |
| No change | 118 | 8% |
| Worse | 280 | 20% |
| Much worse | 21 | 2% |
Among the 330 who credit it with their improvement, here’s how they are now
Credit it means they say it’s one reason they got better.
Where each person was at the end of their story, or in their latest post that says how they are, compared with their worst point.
| Outcome described | People | Share |
|---|---|---|
| Recovered | 5 | 1% |
| Near normal | 12 | 4% |
| Much better | 107 | 32% |
| Somewhat better | 160 | 49% |
| Relapsed | 45 | 14% |
| Outcome unclear | 1 | — |
Did it last?
- 16 of 330 said the benefit of a treatment in this approach wore off (7 of them among the 45 who relapsed).
- 199 of 330 say they still need to keep doing something (not always one in this approach) to stay well.
Everyone · not split by condition
By how ill people were
Only the 1,087 who credit this approach, so people it didn’t help or made worse aren’t here. How they are now is their outcome overall.
| Severity at worst | How they are now | n | Recovered or near normal |
|---|---|---|---|
| Mild | 163 | 25% | |
| Moderate | 302 | 13% | |
| Severe | 424 | 17% | |
| Very severe | 61 | 3% | |
| Not stated | 137 | 19% |
| At worst | Outcome | People | Share |
|---|---|---|---|
| Mild | Recovered | 4 of 163 | 2% |
| Mild | Near normal | 37 of 163 | 23% |
| Mild | Much better | 30 of 163 | 18% |
| Mild | Somewhat better | 78 of 163 | 48% |
| Mild | Relapsed | 14 of 163 | 9% |
| Moderate | Recovered | 6 of 302 | 2% |
| Moderate | Near normal | 35 of 302 | 11% |
| Moderate | Much better | 115 of 302 | 38% |
| Moderate | Somewhat better | 117 of 302 | 39% |
| Moderate | Relapsed | 29 of 302 | 10% |
| Severe | Recovered | 19 of 424 | 4% |
| Severe | Near normal | 53 of 424 | 13% |
| Severe | Much better | 157 of 424 | 37% |
| Severe | Somewhat better | 129 of 424 | 30% |
| Severe | Relapsed | 66 of 424 | 16% |
| Very severe | Near normal | 2 of 61 | 3% |
| Very severe | Much better | 29 of 61 | 48% |
| Very severe | Somewhat better | 22 of 61 | 36% |
| Very severe | Relapsed | 8 of 61 | 13% |
| Not stated | Recovered | 7 of 136 | 5% |
| Not stated | Near normal | 19 of 136 | 14% |
| Not stated | Much better | 31 of 136 | 23% |
| Not stated | Somewhat better | 66 of 136 | 48% |
| Not stated | Relapsed | 13 of 136 | 10% |
Everyone · not split by condition
Treatments in this approach
The bar (How it went) and the line under each name are among everyone on the site who tried it and said how it went, the same numbers as on each treatment’s own page. Recovered and Faded are among the people here who credit it. Grey numbers rest on fewer than 10 people; a faded share in red is a third or more.
Fewer than 3 people here credit these, so they aren’t ranked: Labetalol, Timolol, Pindolol, Sotalol.
20 of the 1,087 people
See all 1,087 stories-
Bedbound with ME/CFS, now housebound and somewhat better with rest and low-dose naltrexone
After about 1.5 years of ME/CFS with push–crash cycles, they became bedbound for two months in mid-2026, getting up only for the bathroom. They improved slowly with four months of rest, low-dose naltrexone, a beta-blocker, compression and salt/fluids. By…
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Long COVID with POTS and brain fog, improved then relapsed, now mostly housebound
A teenager developed POTS, vertigo and brain fog after COVID in 2022, then had a near two-year remission. A reinfection in late 2024 left her disabled, and further infections plus a decline into ME-type crashes with light and sound sensitivity made her…
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Housebound and mostly in bed with ME/CFS, now much better on rapamycin and low-carb diet
Ill for over a decade, Flint 23355 was at worst housebound and mostly in bed. Over the years she improved, crediting a low-carb, high-fat diet, iron infusions and rapamycin at 4 mg, which helped PEM after a direct 6 mg start caused a massive crash; weekly…
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Housebound with ME/CFS and brain fog, now much better with pacing and antihistamines
Ill from March 2020, they were housebound with POTS, brain fog and PEM early on, and in May 2023 said treatments had taken them from about 30% to 70% of normal. Blood thinners, guanfacine, antihistamines, continuous progesterone, pacing and other medications…
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Mostly bedbound with ME/CFS, now somewhat better with fludrocortisone and beta blockers
Kestrel 92313 had ME/CFS for about 15 years, mild at first and severe/mostly bedbound (90–95% bedbound) by early 2026. Fludrocortisone, beta blockers, salt and fluids for POTS were part of measures giving about 10% improvement, and they remained severe and…
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Long COVID left him housebound and unable to work; LDN helped brain fog, then he worsened
A Canadian man in his thirties fell ill with long COVID after an infection in late 2022 and kept working until his condition worsened and he could no longer work. Low-dose naltrexone cleared his brain fog, a beta-blocker helped his POTS, and testosterone…
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Housebound or bedbound with ME/CFS, improved then relapsed after propranolol and LDN
After several viruses in 2019 she worsened from mild to moderate-severe ME/CFS, with ADHD stimulants, work and social overexertion driving crashes. She stopped work in December 2025 and was housebound or bedbound for nine months. Propranolol 40 mg lifted her…
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ME/CFS with PEM, brain fog and pain, somewhat better after ketogenic diet and LDN
Developed ME/CFS after Epstein-Barr more than 15 years before writing, later worsened by long COVID. She described PEM, POTS (later resolved), MCAS, migraines, brain fog and pain, and crashes after exertion. She credited a ketogenic diet, low-dose naltrexone…
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Mostly bedbound for years with ME/CFS, now much better after Abilify and propranolol
They fell ill in June 2020 after a post-operative infection and spent years mostly bedbound, leaving the house once every couple months. Starting high-dose Abilify for psychosis in 2025, then raising propranolol for POTS and adding buspirone and clonidine,…
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Bedbound with severe ME/CFS, now moving toward moderate with pacing and LDN
Ill with ME/CFS since a viral infection at age 8 in 2012, they fluctuated between mild and moderate/severe for over a decade. A virus in early 2025 dropped them from near remission to severe and bedbound, with worse POTS and suspected MCAS. Low-dose…
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Bed-bound then couch-bound with long COVID, now much better with pacing and therapy
A Dutch woman in her mid-30s developed ME/CFS-type long COVID after a reinfection; she spent January 2025 in bed and February couch-bound. Propranolol, which she takes for POTS-related tachycardia, made a huge difference in getting her upright rather than…
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Long COVID bedbound some days, housebound most, now much better with rest and beta blocker
She developed long COVID in December 2020 and over about 2.5 years got back to roughly 80% of normal, working full time. A December 2023 reinfection left her bedbound some days and housebound most, and she went on disability. With rest, time, electrolytes,…
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Mostly bedbound with ME/CFS and daily POTS fainting, now much better with pacing
They developed ME/CFS after a COVID infection and were severe, mostly bedbound and fainting daily from POTS, for about two and a half years. Low-dose naltrexone, POTS medication, creatine and strict pacing helped them reach moderate, around Bell 40, but they…
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Nearly bedbound with long COVID, now close to normal after ganglion blocks and nicotine
A former daily 5K runner, he caught COVID and was nearly bedbound in the second month with dysautonomia and PEM. Over more than two years he tried many treatments, crediting stellate ganglion blocks and nicotine, and was trying rapamycin. He was not fully…
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ME/CFS improved then relapsed to severe, out of bed 5-30 minutes; LDN helped thinking
They had ME/CFS since childhood after atypical pneumonia, moderate for some 17 years until a spontaneous remission let them work and exercise for a few months. They then declined into severe, out of bed 5-30 minutes a day, blaming overexertion, Wellbutrin…
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ME/CFS left them mostly in bed; now somewhat better, beta blockers help them stand
Cardinal 75476 fell ill with COVID in September 2025, had a second infection in December, then overexerted, and has been roughly moderate since: mostly in bed, walking about 100 m, under 400 steps a day. Beta blockers let them stand for a few minutes again.…
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ME/CFS with PEM, bedbound, now somewhat better after stopping inhaler
After long COVID they developed ME/CFS symptoms with PEM, suspected POTS/dysautonomia and asthma, deteriorating over a year from work to sick leave. An asthma glucocorticoid inhaler left them bedbound until they stopped it, after which they improved within…
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Severe ME/CFS, mostly bedbound, now somewhat better with radical rest and pacing
A person in Edinburgh who went from mild ME/CFS to severe and mostly bedbound. After a seven-month flare, they got out of years of rolling PEM with radical rest, pacing, activity diaries and Visible. Crashes became shorter and clearer, but they stayed mostly…
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Mostly bedbound with ME/CFS and POTS, now housebound after tVNS and pacing
Crane 62793, a UK adult in their mid-30s, developed ME/CFS after a COVID infection, with symptoms starting in 2022-2023: first mild then moderate-severe with PEM, brain fog and migraines. A crash in October 2025 left them mostly bed bound and they developed…
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Bedbound with ME/CFS for three years, now much better with methylene blue
Undiagnosed mild ME/CFS for years, Hill 46448 became severe after a concussion and a crash that left her bedbound about three years, needing a power wheelchair and diapers. She credits compounded methylene blue most, alongside POTS drugs, LDN, NAD-ketamine…
The newest 20 people who credit beta-blockers.
20 of the 756 people
See all 756 stories-
Long COVID with POTS and brain fog, improved then relapsed, now mostly housebound
A teenager developed POTS, vertigo and brain fog after COVID in 2022, then had a near two-year remission. A reinfection in late 2024 left her disabled, and further infections plus a decline into ME-type crashes with light and sound sensitivity made her…
-
Long COVID left him housebound and unable to work; LDN helped brain fog, then he worsened
A Canadian man in his thirties fell ill with long COVID after an infection in late 2022 and kept working until his condition worsened and he could no longer work. Low-dose naltrexone cleared his brain fog, a beta-blocker helped his POTS, and testosterone…
-
Bed-bound then couch-bound with long COVID, now much better with pacing and therapy
A Dutch woman in her mid-30s developed ME/CFS-type long COVID after a reinfection; she spent January 2025 in bed and February couch-bound. Propranolol, which she takes for POTS-related tachycardia, made a huge difference in getting her upright rather than…
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Long COVID bedbound some days, housebound most, now much better with rest and beta blocker
She developed long COVID in December 2020 and over about 2.5 years got back to roughly 80% of normal, working full time. A December 2023 reinfection left her bedbound some days and housebound most, and she went on disability. With rest, time, electrolytes,…
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Nearly bedbound with long COVID, now close to normal after ganglion blocks and nicotine
A former daily 5K runner, he caught COVID and was nearly bedbound in the second month with dysautonomia and PEM. Over more than two years he tried many treatments, crediting stellate ganglion blocks and nicotine, and was trying rapamycin. He was not fully…
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Long COVID with severe ME/CFS, mostly housebound, now somewhat better with LDN
She caught COVID-19 in January 2021 and, after years of pushing exercise, went from mild to severe ME/CFS, mostly housebound with PEM, brain fog and breathlessness. CoQ10, acetyl-L-carnitine, acupuncture, metoprolol and low-dose naltrexone (4.5 mg twice…
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Long COVID with dysautonomia, POTS and PEM, somewhat better with pacing and LDN
Ocean 25224 has had long COVID since January 2021, with dysautonomia, POTS, ME/CFS and PEM. They credit HRV-guided pacing, atenolol after metoprolol failed, LDN and a tailored supplement stack for more stable days, though they cannot work and still crash.
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Long COVID with daily migraines and pain, better on Botox and propranolol, then relapsed
Flint 26856 has had long COVID since the first wave in early 2020, when function fell to about 20% of normal with daily migraines, chest and arm pain, panic attacks and memory trouble. Botox, propranolol, tizanidine and lifestyle changes lifted quality of…
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Largely housebound with long COVID for months, now near normal on LDN and propranolol
A woman in New York developed long COVID in October 2022 at age 33 after a May 2022 infection, becoming largely housebound for six to seven months with PEM, brain fog, insomnia, POTS and fatigue. Low-dose naltrexone and propranolol brought her back to a…
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Largely in bed with long COVID, gains on pacing and LDN, then a relapse to 70-80%
A 51-year-old physician caught COVID in September 2025 and developed long COVID with dysautonomia, head pressure, tinnitus and rolling crashes; for months he was largely in bed, able to walk only around the block. Pacing, acceptance and protected sleep…
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Long COVID with brain fog and air hunger, improved then worse again; metoprolol helped
Osprey 80225, then 33, got COVID in November 2024 and worked through it, developing daily adrenaline rushes, head pressure, air hunger, brain fog and digestive problems while doctors called it anxiety. A flu in December 2025 brought everything back worse;…
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Long COVID with passing out, vomiting and migraines, now much better with ketotifen, LDN
Tulip 99250 had Lyme disease and MCAS before COVID in 2020 made everything worse; at the worst they were passing out, vomiting, with frightening migraines and too exhausted to think or walk. Ketotifen, LDN 4 mg and POTS measures helped, then Zepbound from…
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Long COVID at 25% function at worst, now much better after treating migraine and POTS
A bad virus in 2018 led to ME/CFS; Covid in 2020 took them from mild to moderate-severe, and after a booster in early 2022 migraines became daily and at worst they were largely in a dark room at about 25% function. Treating migraine, POTS and MCAS helped; by…
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Housebound with long COVID for months, now much better with metoprolol and cardiac rehab
After COVID in summer 2022 they never recovered and were housebound for months, often too sick to lie down, slowly improving with metoprolol, a stimulant, muscle relaxants, sleep medication and cardiac rehab. By 2024 they were working full time but remained…
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Long COVID with no energy beyond a 60-hour week, nearly normal with a 40-hour schedule
They caught COVID in October 2020 and for two years had no energy beyond a 60-hour-a-week job until a 40-hour schedule helped them stabilise. Low-dose naltrexone, metoprolol and later mestinon calmed their dysautonomia. Low-dose Zepbound started in late 2025…
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Neuro long COVID with dizziness and brain fog, now close to normal after rest and pacing
A woman in her thirties in Germany developed neuro long COVID after a first COVID infection in 2024, with dizziness, brain fog and headaches. She credits radical rest, pacing and a three-month break from work; a first Novavax shot helped clear the last…
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Unable to walk for a few weeks with long COVID, now much better after meditation and LDN
Fjord 60658 caught COVID in March 2020 and long COVID began that June, leaving them unable to walk for a few weeks. Improvement came about two years in, after months of disability leave spent meditating in a dark room, and later nortriptyline, LDN and sleep…
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Mostly bedridden with long COVID, 30% better with time and rest
This Reddit user developed long COVID after a second COVID infection in September 2023; the first two years were mostly bedridden. They credited time, rest, propranolol and occasional Valium for roughly 30% improvement after three years. In October 2026 they…
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Long COVID with brain fog, PEM, insomnia and POTS, now much better with meds and boosters
A Canadian civil engineer, 28, caught COVID in May 2021 and developed long COVID with brain fog, PEM, insomnia and POTS. A Moderna bivalent booster in November 2022 gave about six months of near-complete remission before symptoms returned; later Moderna…
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Long COVID with breathlessness and severe MCAS; keto and NAC helped partly, then relapse
Crane 66255 fell ill with COVID-19 in March 2020 and stayed ill for over six years with breathlessness, neuropathy, insomnia, severe MCAS and kidney problems. Antivirals, keto, fasting, NAC and vitamin D brought partial benefit that faded or lasted only…
The newest 20 people with long COVID who credit beta-blockers.
20 of the 330 people
See all 330 stories-
Bedbound with ME/CFS, now housebound and somewhat better with rest and low-dose naltrexone
After about 1.5 years of ME/CFS with push–crash cycles, they became bedbound for two months in mid-2026, getting up only for the bathroom. They improved slowly with four months of rest, low-dose naltrexone, a beta-blocker, compression and salt/fluids. By…
-
Housebound and mostly in bed with ME/CFS, now much better on rapamycin and low-carb diet
Ill for over a decade, Flint 23355 was at worst housebound and mostly in bed. Over the years she improved, crediting a low-carb, high-fat diet, iron infusions and rapamycin at 4 mg, which helped PEM after a direct 6 mg start caused a massive crash; weekly…
-
Housebound with ME/CFS and brain fog, now much better with pacing and antihistamines
Ill from March 2020, they were housebound with POTS, brain fog and PEM early on, and in May 2023 said treatments had taken them from about 30% to 70% of normal. Blood thinners, guanfacine, antihistamines, continuous progesterone, pacing and other medications…
-
Mostly bedbound with ME/CFS, now somewhat better with fludrocortisone and beta blockers
Kestrel 92313 had ME/CFS for about 15 years, mild at first and severe/mostly bedbound (90–95% bedbound) by early 2026. Fludrocortisone, beta blockers, salt and fluids for POTS were part of measures giving about 10% improvement, and they remained severe and…
-
Housebound or bedbound with ME/CFS, improved then relapsed after propranolol and LDN
After several viruses in 2019 she worsened from mild to moderate-severe ME/CFS, with ADHD stimulants, work and social overexertion driving crashes. She stopped work in December 2025 and was housebound or bedbound for nine months. Propranolol 40 mg lifted her…
-
ME/CFS with PEM, brain fog and pain, somewhat better after ketogenic diet and LDN
Developed ME/CFS after Epstein-Barr more than 15 years before writing, later worsened by long COVID. She described PEM, POTS (later resolved), MCAS, migraines, brain fog and pain, and crashes after exertion. She credited a ketogenic diet, low-dose naltrexone…
-
Mostly bedbound for years with ME/CFS, now much better after Abilify and propranolol
They fell ill in June 2020 after a post-operative infection and spent years mostly bedbound, leaving the house once every couple months. Starting high-dose Abilify for psychosis in 2025, then raising propranolol for POTS and adding buspirone and clonidine,…
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Bedbound with severe ME/CFS, now moving toward moderate with pacing and LDN
Ill with ME/CFS since a viral infection at age 8 in 2012, they fluctuated between mild and moderate/severe for over a decade. A virus in early 2025 dropped them from near remission to severe and bedbound, with worse POTS and suspected MCAS. Low-dose…
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Mostly bedbound with ME/CFS and daily POTS fainting, now much better with pacing
They developed ME/CFS after a COVID infection and were severe, mostly bedbound and fainting daily from POTS, for about two and a half years. Low-dose naltrexone, POTS medication, creatine and strict pacing helped them reach moderate, around Bell 40, but they…
-
ME/CFS improved then relapsed to severe, out of bed 5-30 minutes; LDN helped thinking
They had ME/CFS since childhood after atypical pneumonia, moderate for some 17 years until a spontaneous remission let them work and exercise for a few months. They then declined into severe, out of bed 5-30 minutes a day, blaming overexertion, Wellbutrin…
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ME/CFS left them mostly in bed; now somewhat better, beta blockers help them stand
Cardinal 75476 fell ill with COVID in September 2025, had a second infection in December, then overexerted, and has been roughly moderate since: mostly in bed, walking about 100 m, under 400 steps a day. Beta blockers let them stand for a few minutes again.…
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ME/CFS with PEM, bedbound, now somewhat better after stopping inhaler
After long COVID they developed ME/CFS symptoms with PEM, suspected POTS/dysautonomia and asthma, deteriorating over a year from work to sick leave. An asthma glucocorticoid inhaler left them bedbound until they stopped it, after which they improved within…
-
Severe ME/CFS, mostly bedbound, now somewhat better with radical rest and pacing
A person in Edinburgh who went from mild ME/CFS to severe and mostly bedbound. After a seven-month flare, they got out of years of rolling PEM with radical rest, pacing, activity diaries and Visible. Crashes became shorter and clearer, but they stayed mostly…
-
Mostly bedbound with ME/CFS and POTS, now housebound after tVNS and pacing
Crane 62793, a UK adult in their mid-30s, developed ME/CFS after a COVID infection, with symptoms starting in 2022-2023: first mild then moderate-severe with PEM, brain fog and migraines. A crash in October 2025 left them mostly bed bound and they developed…
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Bedbound with ME/CFS for three years, now much better with methylene blue
Undiagnosed mild ME/CFS for years, Hill 46448 became severe after a concussion and a crash that left her bedbound about three years, needing a power wheelchair and diapers. She credits compounded methylene blue most, alongside POTS drugs, LDN, NAD-ketamine…
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Very severe and bedridden with ME/CFS, now somewhat better with pacing and rest
Osprey 98184 became ill with COVID in December 2022 and declined from mild, active (20,000 steps) to very severe and bedridden after crashes in 2024–25. They credited pacing, rest, mestinon and low-dose ketamine lozenges with slow cognitive improvement from…
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Housebound and off work with ME/CFS, now much better with LDN and pacing
Diagnosed with mild to moderate ME/CFS and POTS in the UK in 2024, after a covid-triggered episode in 2022 and a parasite infection in April 2024. Before starting LDN they had been housebound, used a wheelchair when out and were off work. Low-dose…
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Severe ME/CFS, mostly bedbound, brief gains from ketamine and enoxaparin then relapse
Beacon 76527 was diagnosed with severe ME/CFS in 2014 and stayed mostly bedbound, severe or very severe, for over a decade. A second Pfizer vaccine in 2021 left them 24/7 bedbound for about five months, and they came out of it slowly with strict rest and…
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ME/CFS after long COVID, mostly home and pacing, somewhat better
A 41-year-old Southern California parent who caught COVID in August 2023 developed long COVID with PEM, tachycardia, brain fog and worse migraines. Beta-blockers and migraine medication helped her symptoms, while occupational therapy and aggressive pacing…
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Bedbound and housebound with ME/CFS, now much better with pacing and POTS/MCAS drugs
Diana fell ill at 12 in 1998 and was very severe for about 15 years, bedbound for about four years and housebound for another seven or so. Endometriosis surgery moved them to moderate, and treating POTS and MCAS from late 2024 brought them toward mild.…
The newest 20 people with ME/CFS who credit beta-blockers.