ME/CFS in waves and bedbound for two days, now much better on propranolol and Vyvanse
- Condition
- ME/CFS
- At worst
- Not stated
- Ill before improving or writing
- Not stated
- Last post
- Oct 2025
In their words
- Condition: ME/CFS
CFS has come in waves prob on the low end now
In context ↗ - Now: Much better
I just started propanolol and Vyvanse and it’s life changing ... CFS has come in waves prob on the low end now, but I don’t feel it on this combo.
- Began after: mould or toxic exposure
My apartment may have mold and I also have a cat so this could be contributing.
Summary
Crest 88531 describes CFS that comes in waves, currently on the low end, possibly linked to dust, allergies or mould at home. In February 2025 they started propranolol 20 mg and Vyvanse 30 mg, calling the combination life changing: alert and focused, no longer feeling the CFS on it. In October 2025 they were bed bound for two days with whole-body burning pain, then felt better after vacuuming and taking an antihistamine.
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What they tried
What they credit
Also tried
Their words about each treatment
- propanolol · Helped
Propanolol alone (20mg) is good for my anxiety and probably other things ... The combination makes me alert and focused
In context ↗ - Vyvanse · Helped
Vyvanse alone (30mg) makes me relax and focus, but makes me feel weird socially and I can’t think quickly. The combination makes me alert and focused
In context ↗ - antihistamine · Helped
I vacuumed my whole apartment and took an antihistamine and felt better
In context ↗
Approaches: Beta-blockers · Stimulants
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| — | CFS onset, suspected dust/allergy/mould linkCFS potentially caused by dust / allergiesIn context ↗ | Not stated | |
| 2025-02-04 | started propranolol and Vyvanse, called life changingI just started propanolol and Vyvanse and it’s life changingIn context ↗ | Mild | |
| 2025-10-01 | bed bound two days with whole-body burning pain (suspected dust/mould/allergy exposure)I was basically bed bound for two days my whole body was hurting felt like I was on fire.In context ↗ | Severe | |
| 2025-10-01 | felt better after vacuuming and an antihistamine; CFS on the low endI vacuumed my whole apartment and took an antihistamine and felt better.In context ↗ | Mild | H1 antihistamines (unspecified) |
Adverse events
- Lisdexamfetamine (Vyvanse, Elvanse)“Vyvanse alone (30mg) makes me relax and focus, but makes me feel weird socially and I can’t think quickly.” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Pain & fibromyalgia
my whole body was hurting felt like I was on fire
In context ↗ - Mast cell (MCAS) & allergies
CFS potentially caused by dust / allergies
In context ↗ - Anxiety & low mood
Propanolol alone (20mg) is good for my anxiety
In context ↗
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