Long COVID brain fog and migraine, somewhat better on ivabradine and CGRP drugs
- Condition
- Long COVID
- At worst
- Not stated
- Ill before improving or writing
- 4 years
- Last post
- Oct 2026
In their words
- Condition: Long COVID
Ive had long covid for 4 years and my main symptoms are fatigue, hyperpots, brain fog.
In context ↗ - Now: Somewhat better
It's given me more energy and better sleep ... my main symptoms are fatigue, hyperpots, brain fog
- Began after: COVID
my first and only infection in Oct 2022
In context ↗
Read from 16 of their posts and comments; links to the 15 this page draws on
Summary
Fox 55404 fell ill with long COVID after a single COVID infection in October 2022, with brain fog, a resting heart rate of 120, migraine on 20+ days a month and night sweats. Duloxetine, started in late 2024, lifted mood and cut rage, and ivabradine gave more energy and better sleep than propranolol. Acupuncture helped fatigue and sleep, and CGRP drugs cut migraine to a day or two a month; fatigue, hyperPOTS and brain fog persisted.
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What they tried
What they credit
Also tried
Their words about each treatment
- propranolol, a beta blocker · Helped
I was on propranolol for 2 years and now I've been on ivabradine for 6 months and for me, it's much better.
In context ↗ - duloxetine aka Cymbalta (an SNRI) · Helped a lot
I've found 60mg of Cymbalta (an SNRI) to be the main thing that helps my hair- trigger reactivity and irritability
In context ↗ - Fluoxetine aka Prozac · Worse
It mostly made my heat intolerance way worse and didn't do much else.
In context ↗ - long covid physio and micropacing · Helped
I've had the most success with a long covid physio.
In context ↗ - Garmin for hr and an oura to track sleep · Not said
I got a Garmin for hr and an oura to track sleep
In context ↗ - Perrin Technique · Not said
also started the Perrin Technique w an osteo around the time I started the 60mg dose. Pretty sure it's the Cymbalta that's been helping tho
In context ↗ - pantazoprole (a ppi) · Helped
I started pantazoprole (a ppi) and it stopped the coughing
In context ↗ - acupuncture · Helped a lot
I got huge relief from acupuncture, too. It really helped me fatigue and my sleep.
In context ↗ - Monoferric · Not said
I've read and personally found Monoferric to be an iron infusion with less risk and side effects.
In context ↗ - Compression pants/shorts · Not said
Compression pants/shorts will help as well.
In context ↗ - ivabradine · Helped
now I've been on ivabradine for 6 months and for me, it's much better. It's given me more energy and better sleep.
In context ↗ - alesse · Helped a lot
I take alesse continuously (so no sugar pills) and it's been a miracle for my pmdd which existed prior to LC.
In context ↗ - DGL (deglycinated licorice) supplement · Helped
I also take a DGL (deglycinated licorice) supplement about 30 mins and that helps.
In context ↗ - Mounjaro · Not said
I get way less acid reflux if I take it NOT before bed (like 3pm)
In context ↗ - Qlipta · Helped a lot
Qlipta as a daily preventative which has eliminated my migraine pain days from 20/month to 1-2/ month
In context ↗ - Ubrelvy · Helped
I use Ubrelvy for when I have migraines
In context ↗ - mattress topper · Helped
It's the only thing that has solved my night sweats.
In context ↗ - Novavax vaccine (sometimes known as Nuvaxovid) · Not said
This year's Novavax gave me ZERO side effects!
In context ↗
Approaches: POTS medication · Pacing
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| October 2022 | Long COVID began after a single COVID infectionmy first and only infection in Oct 2022In context ↗ | Moderate | |
| about 1.5 years in (2024) | heat intolerance worsened on fluoxetineIt mostly made my heat intolerance way worse and didn't do much else.In context ↗ | Moderate | |
| October 2024 | started duloxetine; mood improved, rage later reduced by 70%A dose of 30mg really helped my mood and a dose of 60mg reduced my rage by 70%In context ↗ | Moderate | |
| about December 2025 | switched from propranolol to ivabradine; more energy, better sleepfor me, it's much better. It's given me more energy and better sleep.In context ↗ | Moderate | Ivabradine |
| February 2026 | acupuncture relieved fatigue and sleepI got huge relief from acupuncture, too. It really helped me fatigue and my sleep.In context ↗ | Moderate | |
| July 2026 | CGRP migraine drugs cut migraine days from 20+ to 1-2 a monthIt took me from 20+ migraine pain days /month to 1-2.In context ↗ | Mild | |
| October 2026 | still has fatigue, hyperPOTS and brain fog four years inIve had long covid for 4 years and my main symptoms are fatigue, hyperpots, brain fog.In context ↗ | Mild |
Adverse events
- Fluoxetine (Prozac)“Ive had LC since Oct 2022 and tried Fluoxetine aka Prozac about 1.5 years in to this journey. It mostly made my heat intolerance way worse and didn't do much else.” In context ↗ Made symptoms worse
- Duloxetine (Cymbalta)“I had to titrate slowly because the fatigue was a big side effect.” In context ↗ Side effects
- Tirzepatide (Mounjaro, Zepbound)“I get way less acid reflux if I take it NOT before bed (like 3pm) and also don't eat 2 hours before bed.” In context ↗ Gut side effects
- COVID vaccination as treatment“I get awful side effects from moderna and Pfizer but almost nothing from Novavax.” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Brain fog
I have brain fog and memory issues so my neurologist did an MRI
In context ↗ - POTS & dysautonomia
my main symptoms are fatigue, hyperpots, brain fog
In context ↗ - Heart symptoms & palpitations
I have a high heartrate so the cardiologist put me on propranolol
In context ↗ - Headaches & migraine
It took me from 20+ migraine pain days /month to 1-2.
In context ↗ - Anxiety & low mood
a dose of 60mg reduced my rage by 70%
In context ↗ - Sleep problems
It really helped me fatigue and my sleep.
In context ↗ - Temperature regulation
It mostly made my heat intolerance way worse
In context ↗ - Gut problems
I started pantazoprole (a ppi) and it stopped the coughing
In context ↗
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