Long COVID, bedridden after overexertion; somewhat better with LDN and SS-31
- Condition
- Long COVID
- At worst
- Severe (mostly bedbound)
- Ill before improving or writing
- 5 years
- Last post
- Jul 2026
In their words
- Condition: Long COVID
I'm still very ill compared to what I was prior to covid, but the meds I've taken have made all.the difference
In context ↗ - At worst: Severe
before I would be bed bound if I walked a little bit too far ... I went from being unable to make it through the day without regular naps and laying down
- Now: Somewhat better
I am still very fatigued but I can function most days where before I would be bed bound if I walked a little bit too far
In context ↗ - Began after: COVID
I'm still very ill compared to what I was prior to covid
In context ↗
Read from 15 of their posts and comments; links to the 10 this page draws on
Summary
Nightjar 41148, in the UK, had long COVID, with fatigue, PEM and memory loss so bad that slight overexertion left them bedridden for days. Low-dose naltrexone greatly reduced brain fog, SS-31 injections gave lasting energy gains, and the stroke drug Ampasse largely fixed memory problems, though SS-31 was very expensive. They remain very fatigued and ill but can now function most days.
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What they tried
What they credit
Also tried
Their words about each treatment
- LDN · Helped a lot
LDN massively reduced my brain fog. ... LDN dialled down the brain fog significantly day to day.
- SS-31 · Helped a lot
12.5mg of SS-31 for 20 days did the most anything has done for energy. Night and day difference.
In context ↗ - NAD+ injections · Helped
I have had some improvement and relief taking NAD+ and MOTS-C injections.
In context ↗ - Ampasse · Helped a lot
A medication called Ampasse made all the difference and has had results that have lasted long after administration.
In context ↗ - Cerebrolysin · Helped a lot
I took a course of two russian stroke medications, Ampasse and Cerebrolysin, an almost permanent fix.
In context ↗ - Respiratory physio · Helped
Respiratory physio and some other things they offered helped.
In context ↗
Approaches: Peptides · Supplements
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| onset | long COVID onsetI'm still very ill compared to what I was prior to covidIn context ↗ | Not stated | |
| — | bedridden for days after slight overexertionone day of slight over exertion would leave me bed ridden for daysIn context ↗ | Severe | |
| by 2025-04 | LDN cut brain fog but fatigue and PEM persistedLDN massively reduced my brain fog. The fatigue and PEM has not got better to any particularly manageable levelIn context ↗ | Severe | Low-dose naltrexone |
| 2025 | SS-31 course ended need for daily naps and lying downI went from being unable to make it through the day without regular naps and laying down to being able to get through the dayIn context ↗ | Moderate | |
| 2025-12 | Ampasse fixed ongoing memory problems5ml Ampasse for 15 days pretty much fixed my ongoing memory problemsIn context ↗ | Moderate | |
| 2026-02-18 | in a crashJust in a crash currently and don't want to change anything until betterIn context ↗ | Severe | |
| 2026-07-22 | can function most days though still very fatiguedI am still very fatigued but I can function most days where before I would be bed bound if I walked a little bit too farIn context ↗ | Moderate |
Adverse events
- Low-dose naltrexone“Used to take at night, but gave me spicy dreams and sleep issues in general. I now take in the morning” In context ↗ Insomnia from treatment
Symptoms mentioned
Their words about their symptoms
- Brain fog
LDN massively reduced my brain fog
In context ↗ - Post-exertional malaise
The fatigue and PEM has not got better to any particularly manageable level
In context ↗ - Anxiety & low mood
Not spiralling into an unshiftable depression
In context ↗
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