Long COVID sinus tachycardia and brain pressure, somewhat better on ivabradine and PT
- Condition
- Long COVID
- At worst
- Moderate (mostly housebound)
- Ill before improving or writing
- Not stated
- Last post
- Oct 2026
In their words
- Condition: Long COVID
I was throttled with COVID August 2023. I was sick for 18 days and confirmed with Inappropriate Sinus Tachycardia (IST) four months later. It has been a living hell ever since and I barely remember 2024.
In context ↗ - At worst: Moderate
It has been a living hell ever since and I barely remember 2024. ... I am able to move around now without feeling dizzy. I still cannot go on big inclines.
- Now: Somewhat better
I had one day this week where I felt normal for the first time in 2.5yrs ... It has given me a little bit of life back.
- Began after: COVID
I was throttled with COVID August 2023.
Read from 47 of their posts and comments; links to the 25 this page draws on
Summary
After COVID in August 2023 (18 days ill, two hospital visits) they developed inappropriate sinus tachycardia and raised intracranial pressure and barely remember 2024. Ivabradine from December 2023 and autonomic physical therapy cut their tachycardic burden and eased their dizziness. Microdosed tirzepatide and metformin brought days that felt normal and 10k steps in 2026, though big inclines still limit them.
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What they tried
Also tried
Their words about each treatment
- propranolol · Worse
I had rare side effects with propranolol ... the propranolol affected my TSH, T3 AND T4
In context ↗ - diltiazem · Worse
propranolol was terrible for me and I was on diltiazem for 48 hrs. I swelled up like crazy
In context ↗ - Corlanor (ivabradine) · Helped a lot
I have IST from COVID and Ivabradine has helped. I am slowly decreasing my dose
In context ↗ - Magnesium glycinate or magnesium taurate · Helped
Magnesium glycinate or magnesium taurate are game changers for tachycardia
In context ↗ - CoQ10 · Helped
The CoQ10 helps the magnesium absorb better
In context ↗ - melatonin · Helped
the melatonin gets rid of my primary stabbing headache (thanks COVID)
In context ↗ - MyCommunity Comprehensive Mushroom Blend · Helped
I find that taking MyCommunity Comprehensive Mushroom Blend is helpful to boost immunity
In context ↗ - Slynd (progesterone only pill) · Worse
Slynd is derived from a loop diuretic and dumps sodium. I learned that the hard way!
In context ↗ - Cipro · Much worse
Cipro messed me up for years. Check into a sensitivity test.
In context ↗ - compression socks · Worse
I also had issues with compression socks. Wearing them significantly increased my resting heart rate
In context ↗ - parasympathetic and vestibular physical therapy · Helped a lot
I have been going to parasympathetic PT for 11 months. It has helped to reduce my tachycardic burden from 70%, to 46% and now 13%
In context ↗ - metformin · Helped
I feel like the metformin helps with brain fog
In context ↗ - tirzepatide · Helped
The lil bae dose .25mg helped me go on a hike last week without any issues. I also had actually energy to do things.
In context ↗ - meditation · Helped
Meditation is also very powerful in my experience.
In context ↗
Approaches: GLP-1 drugs · POTS medication · Other drugs and medicines
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. The chart starts 10 months after onset: the story doesn’t say how ill they were before that. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| 2024 | Inappropriate sinus tachycardia and raised intracranial pressure; barely remembers the yearIt has been a living hell ever since and I barely remember 2024. Prior to COVID, I was active and hiking at high altitude.In context ↗ | Moderate | |
| February 2025 | Started physical therapy focused on calming the autonomic systemI started going to PT for a shoulder injury and mentioned to my PT that I have autonomic dysfunction.In context ↗ | Moderate | |
| September 2025 | Eight months of parasympathetic and vestibular PT reduced tachycardia; no longer dizzy moving aroundI feel like my IST symptoms are getting better with parasympathetic and vestibular physical therapy.In context ↗ | Mild | |
| late 2025 | Setback after starting a progesterone-only contraceptiveI had a great Summer with a huge drop then has a setback taking a progesterone only contraception that I gave since stopped.In context ↗ | Mild | |
| January 2026 | Hiked stairs and walked 10k steps on microdosed tirzepatide plus metforminI went on a hike with multiple stairs for the first time since this Summer. ... I also walked 10k steps two days beforeIn context ↗ | Mild | Tirzepatide (Mounjaro, Zepbound) |
| 14 January 2026 | 0.5 mg tirzepatide drove IST into high gear with blood pressure and blood sugar problemsThis .5mg dose drove my IST into high gear, caused blood pressure and blood sugar issues.In context ↗ | Mild | |
| October 2026 | Low-dose metformin and tirzepatide; brain fog better, days that feel normalI take metformin and glp-1. I low dose both. 250mg split 2x/day. It helps with brain fog. I also split dose tirzepatide 1.45 split 2x/week.In context ↗ | Mild | Tirzepatide (Mounjaro, Zepbound) |
Adverse events
- Ciprofloxacin (Cipro)“Cipro messed me up for years. Check into a sensitivity test.” In context ↗ Made symptoms worse
- Propranolol (Inderal)“I had headaches and dizziness every day as well.” In context ↗ Side effects
- Propranolol (Inderal)“It also did the opposite and made me feel really sad.” In context ↗ Mood or psychiatric effects
- Propranolol (Inderal)“the propranolol affected my TSH, T3 AND T4. I have hypothyroidism is and it doubled my values, so I gained a rapid amount of weight.” In context ↗ Other
- Diltiazem (Cardizem)“I was on diltiazem for 48 hrs. I swelled up like crazy.” In context ↗ Side effects
- Progestin-only birth control (mini pill, implant or shot)“I will say that Slynd made me sad and gave me a sense of dread, which I was not aware of until I stopped taking it.” In context ↗ Mood or psychiatric effects
- Progestin-only birth control (mini pill, implant or shot)“after COVID with IST/POTS I was peeing non-stop and my sodium was super low.” In context ↗ Refeeding or deficiency problems
- “I used to get SUPER nauseous and could not function for two days after.” In context ↗ Side effects
- Tirzepatide (Mounjaro, Zepbound)“This .5mg dose drove my IST into high gear, caused blood pressure and blood sugar issues.” In context ↗ Heart rhythm problems
- Tirzepatide (Mounjaro, Zepbound)“Going to .5mg kicked my ass. I had racing rate, headache, chest pain, breathlessness, etc.” In context ↗ Side effects
- Tirzepatide (Mounjaro, Zepbound)“I also had low blood sugar. My autonomic system went bonkers bananas.” In context ↗ Other
- Tirzepatide (Mounjaro, Zepbound)“It does irritate the heck out of my heart though, so I am still taking ivabradine.” In context ↗ Heart rhythm problems
- Metformin“I had heart palpations at 250mg, so split the pills.” In context ↗ Heart rhythm problems
- Progestin-only birth control (mini pill, implant or shot)“I had a great Summer with a huge drop then has a setback taking a progesterone only contraception that I gave since stopped.” In context ↗ Made symptoms worse
- Ivabradine“I am slowly decreasing my dose because my body has gotten used to it and lowering my BP.” In context ↗ Low blood pressure or fainting
- Compression garments“I also had issues with compression socks. Wearing them significantly increased my resting heart rate, which I don't need with IST.” In context ↗ Heart rhythm problems
Symptoms mentioned
Their words about their symptoms
- Heart symptoms & palpitations
I have Inappropriate Sinus Tachycardia (IST) thanks to COVID. My RHR while sleeping was 105 before I was medicated.
In context ↗ - Brain fog
I feel like the metformin helps with brain fog
In context ↗ - Headaches & migraine
I am seeing a Neurologist next Friday for the fun migraines!
In context ↗ - Tinnitus
I don't have the whooshing sound in my ear anymore or wake up with headaches if I am not elevated at night.
In context ↗
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