How it went
Did it last?
- 8 of 31 said the benefit wore off (including the 2 who relapsed).
- 4 of 31 needed to keep doing it to stay well.
Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.
| Outcome described | Accounts | Share |
|---|---|---|
| Full recovery | 1 | 3% |
| Near-full | 2 | 6% |
| Substantial | 12 | 39% |
| Partial | 12 | 39% |
| Relapsed | 2 | 6% |
| No benefit | 2 | 6% |
By how ill people were
| Severity at worst | How it went | n | Recovered |
|---|---|---|---|
| Mild | 1 | 0% | |
| Moderate | 3 | 0% | |
| Severe | 15 | 13% | |
| Very severe | 5 | 20% |
7 accounts don’t say how ill the person was.
How often it comes up
Posts that mention CoQ10 / ubiquinol, per 1,000 posts each year. Hover a point for the count.
Show as a table
| Year | Posts mentioning it | All posts | Per 1,000 |
|---|---|---|---|
| 2009 | 3 | 184 | 16.3 |
| 2010 | 5 | 682 | 7.3 |
| 2011 | 5 | 704 | 7.1 |
| 2012 | 8 | 1,491 | 5.4 |
| 2013 | 12 | 1,995 | 6.0 |
| 2014 | 20 | 2,707 | 7.4 |
| 2015 | 28 | 2,566 | 10.9 |
| 2016 | 37 | 2,023 | 18.3 |
| 2017 | 15 | 3,381 | 4.4 |
| 2018 | 98 | 2,523 | 38.8 |
| 2019 | 8 | 1,637 | 4.9 |
| 2020 | 18 | 3,318 | 5.4 |
| 2021 | 5 | 2,469 | 2.0 |
| 2022 | 3 | 1,871 | 1.6 |
| 2023 | 12 | 2,362 | 5.1 |
| 2024 | 6 | 2,176 | 2.8 |
| 2025 | 2 | 1,349 | 1.5 |
| 2026 (so far) | 1 | 899 | 1.1 |
Posts in the forum threads and blog comments we archived, 34,337 in all, counted per year. A mention means the post names the treatment, not that the writer took it. These pages all contain a recovery story, so they show what those communities discussed, not everyone with ME/CFS or long COVID. All trends
All 31 accounts
-
On the road to recovery from Long Covid
Lauren combined nicotine patches at one-eighth of a patch daily through December with a broad daily supplement regimen, including CoQ10 100mg, Ionic Fulvic Acid 1ml three times a day, Hawthorn Leaves 5ml, and products like Adrenal Complex, Adreno Active,…
-
Recovery Protocol Cheat Sheet
Christy's posted recovery protocol lists an extensive regimen: pre-protocol, three months of Eliquis 5 mg daily and clopidogrel 75 mg daily; from February 2024 a "foundation" of nutritional antivirals including matcha green tea, coconut oil, unpasteurized…
-
Treatments. Yes, they do exist.
In this follow-up post, Encephalogirl (Michelle) lists an expanded regimen: low-dose naltrexone, low-dose Abilify, guanfacine, about nine months of tenofovir as part of a planned minimum one-year antiviral course, six weeks of low-dose rapamycin at 1mg once…
-
Why inactive ingredients can be a gamechanger
Christy's treatment here is CoQ10 (Qunol brand): she started with 50 mg gummies (though the bottle recommended 100 mg) last winter, then switched to a liquid "Superior Absorption" formulation that let her tolerate higher doses without side effects, which she…
-
Radical Rest and Beyond
The author of Encephalogirl (who signs as Michelle) treats her ME/CFS-related dysautonomia and POTS with guanfacine and low-dose Abilify (titrated from 0.5mg down to 0.25mg after migraines, then back up to 0.5mg), an increased dose of low-dose naltrexone, a…
-
Good signs from coq10 - now what? (Mary)
Mary said 4,000 to 5,000mg of branched-chain amino acids daily, followed since 2014, cut her post-exertional malaise recovery time by more than half and improved her energy, with CoQ10 adding a further noticeable effect. She notes cheaper BCAA brands worked…
-
[Case study] CFS/ME remission story severe patient [2008]
A severe ME/CFS patient documented in a 2008 case report used a year of tapering immunoglobulin dosing alongside gut-repair supplements and antibiotic treatment for mycoplasma, progressing from severe to mild over the 12 months of treatment. Immunoglobulin…
-
Good signs from coq10 - now what?
Frogsquid13 initially reported good effects from 200mg of ubiquinol, including increased energy and mood. About six weeks later the same poster updated the thread to say the benefit had stopped working after a few weeks, calling it quite cruel to have…
-
List of ME/CFS Recovery and Improvement Stories (page 4 discussion)
crowtor, who progressed from bed-bound to housebound, used three separate targeted interventions: a low-flow oxygen concentrator for brain fog, a bilevel ResMed AirCurve machine for sleep, and very-high-dose ubiquinol plus CoQ10 to blunt PEM. Each addressed…
-
Improvements Reported by fT3g0/Elizabeth-style Case (unnamed woman)
Relayed secondhand by forum member fT3g0 from a YouTube video, this unnamed woman's recovery was credited to ubiquinol/CoQ10 supplementation, ozone therapy, and removal of infected wisdom teeth. The source video was not fetched directly, so duration of…
-
CBT for CFS: Luke Shares His Experience and Recovery
Luke combined self-directed CBT (working through his own negative thought patterns rather than with a therapist) with a methylation protocol developed by Rich Von Konynenburg (B vitamins plus folic acid), guidance from two books -- Kristina Downing-Orr's…
-
Mitochondrial and Energy Metabolism Dysfunction in ME/CFS - Myhill, Booth and McLaren-Howard Papers
MrTwoToedSloth, mostly housebound and limited to about one activity a week before a week-long flare-up, assembled a broad mitochondrial-support stack (CoQ10, acetyl-L-carnitine, nicotinamide riboside, creatine, D-ribose and more) and noticed improvement at…
-
From brain fog to clarity in 30 minutes
A five-supplement mitochondrial stack -- ubiquinol, nicotinamide riboside, fursultiamine, dichloroacetate and PQQ -- reportedly clears his brain fog within about 30 minutes of dosing and gets him to "close to normal" function from a mild/SEID baseline. He is…
-
Huge energy today with Grapefruit and Ubiquinol (Coenzyme Q10). We'll see about tomorrow.
Adding fresh grapefruit around ubiquinol 300mg twice daily was followed within days by being able to run errands to two stores in a morning, do housework, and raise treadmill tolerance from 2.8mph/10min to 3.0mph in 30-minute increments, after about a decade…
-
Treating patients suffering from (ME/CFS) with sodium dicholoracetate
Dichloroacetate (sodium DCA) was taken at 333 mg twice daily, alongside fursultiamine, nicotinamide riboside and ubiquinol, for about two weeks at the time of posting. The account does not state prior illness duration or severity. After roughly two weeks the…
-
Successful Pilot Study Treating PDH Deficiency in ME/CFS (B1 / CoQ10 / ALA / Algae + HOA)
Thiamine injections (with oral benfotiamine also tried), as part of a broader personal supplement stack, improved heavy limbs, muscle twitching, energy, post-meal exhaustion and brain fog. By her own account, "I'm not cured, I just can function better" -- a…
-
Gaps diet put me in direction to recovery
Diagnosed with ME/CFS and fibromyalgia and bedbound by April 2012, she began the GAPS introduction diet with VSL#3 probiotic, enemas, CoQ10, B12 and vitamin C. Within two weeks she started improving slowly, and over roughly two years on the diet she went…
-
3 kings to lift you
From sleeping 22 hours a day and considering suicide about six years into illness, this poster describes a large, years-long stack - pulsed steroids, noopept-based nootropics, experimental NSI-189, and roughly twenty daily supplements - restoring the ability…
-
My recovery after my one and only crash.
Combined a strict elimination diet (no gluten, dairy, processed food or fructose) with Lyrica at 225mg per day, low-dose naltrexone, ketotifen, antihistamines, B12 with methylfolate, rifaximin plus neomycin for SIBO, hyperbaric oxygen, and later tDCS.…
-
Did MitoQ Mend Us? A Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS) CoQ10 Trial
MitoQ at 10mg per day was, in this ME/CFS patient's words, "extremely helpful" and, she said, the first drug to keep her from crashing. Illness duration before the trial is not stated. She enrolled in a non-placebo-controlled arm of a formal MitoQ trial but…
-
Did MitoQ Mend Us? A Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS) CoQ10 Trial
MitoQ caused severe insomnia in this ME/CFS patient (diagnosed at OMI) after a single 10mg dose, and moderate-to-severe insomnia again when a lower 5mg dose was tried separately. No fatigue or functional benefit is reported from either trial. The person…
-
Combination of Supplements Allows Me to Work and Exercise - But causes extreme Gastritis
Built a roughly 60-item daily supplement stack (B12, NADH, high-dose antioxidants/glutathione, SAM-e, CoQ10, glandulars, ribose, phosphatidylserine and more) over three-plus years of trial and error for CFS, fibromyalgia and Hashimoto's. Says the combination…
-
Successful Treatment of CFS - Oriental Medicine
After 30 years of illness described as "sheer agony," started a traditional Chinese spleen tonic together with CoQ10 and alpha-lipoic acid. Says that within days she felt "much more energetic" and within one to two weeks felt "the way I'd always thought…
-
90% cured from bed bound with Histrelief / Histame / Daosin
After being diagnosed with a DAO deficiency, xlynx reports "90% recovery" from being bed/wheelchair-bound, with obvious effects from the first week and full effect by about 3 months, durable for 6 months at the time of posting. She frames it as ongoing…
-
Freddd - have increased energy on your protocol!
After 13 years of severe exercise intolerance, including 4 years on the Simplified Methylation Protocol with negative effects, she switched to a carnitine-fumarate-centered regimen with methyl-B12 injections and Metafolin. She initially felt "more normal,…
-
What treatments HAVE ACTUALLY helped?
Combined a large stack of B12 injections, CoQ10, Fibroenergy, amino acids, SAMe, magnesium, prescription vitamin D, Synthroid, three years of low-dose Minocin, three months of antivirals, and a gluten-free diet, without singling out one component as key. Now…
-
What treatments HAVE ACTUALLY helped?
Took a mitochondrial-support stack of CoQ10, B3, magnesium and zinc after being, in her words, "totally bed ridden with super low ATP." Reports being "much better than I was," a substantial gain, but says she is "still mostly house bound" and was actively…
-
Stages of Recovery - personal experience
Followed Dr Myhill's standard protocol (B3, B12, magnesium, CoQ10, 15g/day L-glutamine, 10g/day BCAAs, 1g/day malic acid) starting Nov/Dec 2007, combined with an elimination diet of mainly white rice and chicken, FIR sauna detox, and Buteyko breathing. Went…
-
My complete protocol - recovering well from bad 7 years+ CFS
Ran a broad two-year self-built protocol - high-dose B vitamins, vitamin D3, D-ribose, CoQ10, acetyl-L-carnitine, a sublingual/nasal B12-folate methylation stack, amino acids, Buteyko breathing, infrared sauna and transdermal magnesium - layered onto months…
-
? for those who feel "totally healthy" out of the blue
Made dietary changes, eliminated food intolerances, and used amino acid supplements, CoQ10 and salt loading (possibly along with Emergen-C or guarana). Experienced repeated episodes of feeling "completely healthy" lasting from hours up to 3 weeks, including…
-
Anybody taking MitoQ?
MitoQ was taken orally for about 4 to 5 months, with no dose specified in the post. Illness duration before treatment is not stated. The person reports it simply "didn't seem to help" and was expensive, so they discontinued it. They switched back to regular…